Reactome | PHF20L1 [nucleoplasm]

PHF20L1 [nucleoplasm]

Stable Identifier

R-HSA-9828235

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PHD finger protein 20-like protein 1, P20L1_HUMAN

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- Epigenetic regulation of gene expression (Homo sapiens)
  - Epigenetic regulation by WDR5-containing histone modifying complexes (Homo sapiens)
    - Formation of WDR5-containing histone-modifying complexes (Homo sapiens)
      - Formation of the NSL complex (Homo sapiens)
        
        NSL [nucleoplasm] (Homo sapiens)
        
        NSL (PHF20L1) [nucleoplasm] (Homo sapiens)
        
        PHF20L1 [nucleoplasm] (Homo sapiens)
        
        PHF20, PHF20L1 [nucleoplasm] (Homo sapiens)
        
        PHF20L1 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:A8MW92 PHF20L1

Gene Names

PHF20L1, CGI-72

Chain

chain:1-1017

Reference Genes

BioGPS Gene:51105 PHF20L1

COSMIC (genes):PHF20L1 PHF20L1

CTD Gene:51105 PHF20L1

dbSNP Gene:51105 PHF20L1

ENSEMBL:ENSG00000129292 PHF20L1

ENSEMBL_homo_sapiens_GENE:ENSG00000129292.21 PHF20L1

HGNC:24280 PHF20L1

KEGG Gene (Homo sapiens):51105 PHF20L1

Monarch:51105 PHF20L1

NCBI Gene:51105 PHF20L1

OMIM:620050 PHF20L1

UCSC:A8MW92 PHF20L1

Reference Transcript

Other Identifiers

11727528_a_at

11727529_at

11727530_a_at

11727531_at

11733292_a_at

11733293_at

11733294_at

11742454_s_at

1554472_PM_a_at

1554472_a_at

17072799

226942_PM_at

226942_at

227523_PM_s_at

227523_s_at

230098_PM_at

230098_at

231967_PM_at

231967_at

3116536

3116537

3116539

3116541

3116545

3116546

3116548

3116552

3116555

3116559

3116560

3116561

3116562

3116563

3116567

3116569

3116573

3116578

3116582

3116583

3116589

3116592

3116593

3116595

3116596

3116599

3116601

3116602

3116603

3116604

3116605

3116606

3116607

3116608

43564_at

48594_at

51105

59498_at

62138_at

66940_at

8148358

A_23_P134786

A_24_P403303

A_33_P3278906

GE521413

GE58653

GE83334

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006351

GO:0006355

GO:0006357

GO:0030163

GO:0032435

GO:0042177

GO:0043226

GO:0044545

GO:0046872

GO:0140034

HMNXSV003026773

HMNXSV003039127

Hs.170335.0.A1_3p_at

Hs.318725.1.S1_3p_s_at

Hs.318725.2.S1_3p_at

Hs.44159.0.S1_3p_at

Hs2.318725.2.S1_3p_s_at

ILMN_1732985

ILMN_2268618

ILMN_2361186

PH_hs_0022123

TC08000768.hg

Participates

as a component of

NSL (PHF20L1) [nucleoplasm] (Homo sapiens)

as a member of

PHF20, PHF20L1 [nucleoplasm] (Homo sapiens)

Inferred To

MBD-R2 [nucleoplasm] (Drosophila melanogaster)

Phf20l1 [nucleoplasm] (Mus musculus)

Phf20l1 [nucleoplasm] (Rattus norvegicus)

PHF20L1 [nucleoplasm] (Canis familiaris)

Ghost homologue of PHF20L1 [nucleoplasm] (Bos taurus)

Cross References

RefSeq

NP_940915.1, NP_057102.4, XP_016869006.1

OpenTargets

ENSG00000129292

GeneCards

A8MW92

HPA

ENSG00000129292-PHF20L1

Ensembl

ENSP00000338269, ENST00000337920, ENSP00000378784, ENST00000395386, ENSP00000482945, ENSG00000129292, ENST00000622263

PRO

A8MW92

Pharos - Targets

A8MW92

PDB

6L1F, 2EQU, 2EQM, 6L1C, 2JTF, 6L0X, 6L10, 6L1P, 6L1I

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62805 H4C1	17	polySUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531) monoSUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) HIST1H4A [extracellular region] (R-HSA-977569) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652) HIST1H4 [nucleoplasm] (R-HSA-181902)	0.558	2
UniProt:Q7Z3B3 KANSL1	1	KANSL1 [nucleoplasm] (R-HSA-3321875)	0.527	3