SOX17 binds the PDPN gene

Stable Identifier
R-HSA-9827994
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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SOX17 binds the PDPN gene
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SOX17 binds the gene encoding Podoplanin (PDPN) and activates its expression during the differentiation of human primordial germ cells (PGCs) from embryonic stem cells in vitro (Tang et al. 2022). PDPN protein, expressed in the plasma membrane, mediates cell adhesion and migration (reviewed in Dang et al. 2014).
Literature References
PubMed ID Title Journal Year
35411086 Sequential enhancer state remodelling defines human germline competence and specification

Castillo-Venzor, A, Tang, WWC, Surani, MA, Sun, D, Gruhn, WH, Penfold, CA, Kobayashi, T, Irie, N, Morgan, MD

Nat Cell Biol 2022
Participants
Input
Output
Participates
as an event of
Authored
May, B  (2023-02-09)
Reviewed
Tam, PPL  (2023-05-03)
Created
May, B  (2023-02-09)
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