HES7 binds the LFNG gene

Stable Identifier
R-HSA-9824196
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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HES7 binds the LFNG gene
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The Hairy and enhancer of split 7 (HES7) protein binds the promoter of the Lunatic fringe (LFNG) gene and represses activation of LFNG by NOTCH signaling (inferred from mouse homologs). Oscillatory expression of HES7 (inferred from the mouse homolog in Bessho et al. 2001) and repression of NOTCH signaling by LFNG (inferred from chicken homologs in Dale et al. 2003) cause oscillatory expression of LFNG during somite formation.
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Hes7 binds the Lfng gene (Mus musculus)
Authored
Chalamalasetty, RB  (2022-11-09)
Yamaguchi, TP  (2022-11-09)
Reviewed
May, B  (2023-05-12)
Created
May, B  (2023-01-18)
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