RBPJ:NICD1 and MSGN1 bind the LFNG gene

Stable Identifier
R-HSA-9824182
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Mesogenin1 (MSGN1) binds the upstream regulatory region of the Lunatic fringe (LFNG) gene (inferred from mouse homologs). MSGN1 binds both the block A conserved promoter element that regulates expression in the posterior presomitic mesoderm and the block B conserved element that regulates expression in the anterior presomitic mesoderm (inferred from mouse homologs). RBPJ and the Notch intracellular domain (NICD) fragment produced by NOTCH1 signaling bind the block A conserved element (inferred from mouse homologs).
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