deadenylated mRNP regulated by BTG4 [cytosol]

Stable Identifier
R-HSA-9822333
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
mRNA's that are ready for translation have a circular structure caused by interaction between PABP bound to the 3' poly(A) tail and the eIF4E-eIF4G-PAIP complex bound to the 7-methylguanosine cap. The interaction between poly(A)-PABP and the eIF4G-eIF4E complex stimulates affinity of eIF4E for the cap and improves translation.
Participants
Participates
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