Reactome | HCFC2 [nucleoplasm]

HCFC2 [nucleoplasm]

Stable Identifier

R-HSA-9821232

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Host cell factor 2, HCFC2_HUMAN, HCF2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y5Z7 HCFC2

Gene Names

HCFC2

Chain

chain:1-792

Reference Genes

BioGPS Gene:29915 HCFC2

COSMIC (genes):HCFC2 HCFC2

CTD Gene:29915 HCFC2

dbSNP Gene:29915 HCFC2

ENSEMBL:ENSG00000111727 HCFC2

ENSEMBL_homo_sapiens_GENE:ENSG00000111727.12 HCFC2

HGNC:24972 HCFC2

KEGG Gene (Homo sapiens):29915 HCFC2

Monarch:29915 HCFC2

NCBI Gene:29915 HCFC2

OMIM:607926 HCFC2

UCSC:Q9Y5Z7 HCFC2

Reference Transcript

RefSeq:NM_013320.2 HCFC2

Other Identifiers

11724545_at

11724546_at

16756136

219484_PM_at

219484_at

235264_PM_at

235264_at

29915

3429407

3429410

3429411

3429414

3429416

3429417

3429418

3429420

3429421

3429422

3429424

3429425

3429428

3429429

3429430

3429431

3429432

3429433

3429434

3429435

3429436

3429437

3429439

46110_at

58124_at

58762_r_at

7958158

A_14_P127030

A_14_P135104

A_23_P25403

A_32_P85539

A_33_P3250018

GE58517

GO:0000122

GO:0002376

GO:0003712

GO:0003713

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005886

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0006357

GO:0016032

GO:0016604

GO:0023052

GO:0034139

GO:0035097

GO:0043226

GO:0044665

GO:0045893

GO:0048188

GO:0071339

GO:0098542

GO:0140110

GO:0140374

GO:1902615

HMNXSV003006343

Hs.110376.0.A1_3p_at

ILMN_1674297

PH_hs_0003642

TC12000807.hg

g7019404_3p_at

Participates

as a component of

as a member of

HCFC1,HCFC2 [nucleoplasm] (Homo sapiens)

Inferred To

Hcfc2 [nucleoplasm] (Mus musculus)

Hcfc2 [nucleoplasm] (Rattus norvegicus)

HCFC2 [nucleoplasm] (Bos taurus)

HCFC2 [nucleoplasm] (Canis familiaris)

HCFC2 [nucleoplasm] (Gallus gallus)

HCFC2 [nucleoplasm] (Sus scrofa)

hcf-1 [nucleoplasm] (Caenorhabditis elegans)

Hcf [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_037452.1

OpenTargets

ENSG00000111727

GeneCards

Q9Y5Z7

HPA

ENSG00000111727-HCFC2

Ensembl

ENST00000544223, ENST00000229330, ENSG00000111727, ENSP00000442942, ENSP00000229330

PRO

Q9Y5Z7

Pharos - Targets

Q9Y5Z7

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.725	4
UniProt:P14316 IRF2	2	IRF2 [cytosol] (R-HSA-1015681) IRF2 [nucleoplasm] (R-HSA-994031)	0.643	3
UniProt:Q03164 KMT2A	6	KMT2A [cytosol] (R-HSA-9818584) KMT2A(2719-3969) [cytosol] (R-HSA-9818590) KMT2A(1-2718) [cytosol] (R-HSA-9818597) KMT2A [nucleoplasm] (R-HSA-1183223) KMT2A(1-2718) [nucleoplasm] (R-HSA-9818591) KMT2A(2719-3969) [nucleoplasm] (R-HSA-9818593)	0.623	5
UniProt:Q15291 RBBP5	1	RBBP5 [nucleoplasm] (R-HSA-1629836)	0.564	3
UniProt:P11142 HSPA8	10	Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [cytosol] (R-HSA-264476)	0.527	3
UniProt:Q9UMN6 KMT2B	5	KMT2B [cytosol] (R-HSA-9818624) KMT2B(2-2062) [cytosol] (R-HSA-9818621) KMT2B(2063-2715) [cytosol] (R-HSA-9818626) KMT2B(2063-2715) [nucleoplasm] (R-HSA-9818623) KMT2B(2-2062) [nucleoplasm] (R-HSA-9818620)	0.527	3
UniProt:Q92560 BAP1	1	BAP1 [nucleoplasm] (R-HSA-5689665)	0.527	2
UniProt:P17987 TCP1	1	TCP1 [cytosol] (R-HSA-390448)	0.527	3
UniProt:Q9UBL3 ASH2L	1	ASH2L [nucleoplasm] (R-HSA-1629834)	0.527	4
UniProt:O15047 SETD1A	1	SETD1A [nucleoplasm] (R-HSA-3239027)	0.527	4
UniProt:O15294 OGT	2	OGT [nucleoplasm] (R-HSA-3321845) OGT [cytosol] (R-HSA-9687814)	0.527	3
UniProt:Q8NFC6 BOD1L1	1	BOD1L1 [nucleoplasm] (R-HSA-8954547)	0.527	4

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