Reactome | ST6GALNAC6 [Golgi membrane]

ST6GALNAC6 [Golgi membrane]

Stable Identifier

R-HSA-981855

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6, SIA7F_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
      - Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
        
        Sialic acid metabolism (Homo sapiens)
        
        ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) (Homo sapiens)
        
        ST6GALNAC1-6 [Golgi membrane] (Homo sapiens)
        
        ST6GALNAC6 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q969X2 ST6GALNAC6

Gene Names

ST6GALNAC6, SIAT7F, UNQ708/PRO1359

Chain

chain:1-333

Reference Genes

BioGPS Gene:30815 ST6GALNAC6

COSMIC (genes):ST6GALNAC6 ST6GALNAC6

CTD Gene:30815 ST6GALNAC6

dbSNP Gene:30815 ST6GALNAC6

ENSEMBL:ENSG00000160408 ST6GALNAC6

HGNC:23364 ST6GALNAC6

KEGG Gene (Homo sapiens):30815 ST6GALNAC6

Monarch:30815 ST6GALNAC6

NCBI Gene:30815 ST6GALNAC6

OMIM:610135 ST6GALNAC6

UCSC:Q969X2 ST6GALNAC6

Reference Transcript

Other Identifiers

0003940079

11718363_a_at

11718364_a_at

11749989_a_at

17098642

222571_at

30815

3226159

3226161

3226162

3226164

3226165

3226166

3226168

3226169

3226170

3226172

3226173

3226175

3226177

3226180

48111_at

8164304

8180339

A_23_P315892

GE53878

GO:0000139

GO:0001574

GO:0001665

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005794

GO:0005886

GO:0005975

GO:0006464

GO:0006486

GO:0006629

GO:0006677

GO:0006687

GO:0008150

GO:0008373

GO:0009058

GO:0009100

GO:0009311

GO:0009312

GO:0009988

GO:0016020

GO:0016021

GO:0016740

GO:0016757

GO:0034641

GO:0043226

GO:0097503

HMNXSV003042507

HMNXSV003046910

HMNXSV003053493

Hs.109672.0.S2_3p_at

ILMN_1691736

PH_hs_0006050

TC09002921.hg

Participates

as a member of

ST6GALNAC1-6 [Golgi membrane] (Homo sapiens)

Inferred To

st6galnac6 [Golgi membrane] (Danio rerio)

st6galnac6 [Golgi membrane] (Xenopus tropicalis)

ST6GALNAC6 [Golgi membrane] (Bos taurus)

ST6GALNAC6 [Golgi membrane] (Canis familiaris)

ST6GALNAC6 [Golgi membrane] (Gallus gallus)

St6galnac6 [Golgi membrane] (Mus musculus)

St6galnac6 [Golgi membrane] (Rattus norvegicus)

Cross References

RefSeq

XP_011516912.1, XP_016870156.1, NP_001273928.1, XP_016870154.1, XP_016870155.1, XP_011516913.1, NP_038471.2, NP_001273929.1, NP_001273930.1, NP_001273932.1, XP_016870148.1, NP_001273931.1

OpenTargets

ENSG00000160408

HPA

ENSG00000160408-ST6GALNAC6

GeneCards

Q969X2

Ensembl

ENST00000373142, ENSP00000291839, ENSP00000362237, ENST00000373141, ENSP00000362235, ENSP00000362234, ENSP00000477575, ENST00000291839, ENST00000622357, ENSG00000160408, ENSP00000362239, ENST00000373146, ENST00000373144

PRO

Q969X2

Pharos - Targets

Q969X2

GlyGen

Q969X2

HMDB Protein

HMDBP03365

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P54253 ATX1			0.666	7
UniProt:Q86W74-2 ANKRD46			0.556	3
UniProt:Q7Z4F1 LRP10	1	LRP10 [plasma membrane] (R-HSA-2424275)	0.556	3