NFE2L2 regulating inflammation associated genes

Stable Identifier
R-HSA-9818026
Type
Pathway
Species
Homo sapiens
Compartment
ReviewStatus
3/5
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Subpathway representing inflammatory genes regulated by NFE2L2. NFE2L2 plays a pivotal role in regulating inflammation directly (by regulating inflammation-related genes like CCL2, IL8) and indirectly (through the HO-1-NFKB axis). This role of NFE2L2 plays a role in inflammatory diseases and expands NFE2L2 role beyond the antioxidant system. (Ahmed et al, 2017; Saha et al, 2020)
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