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CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds CBL
Stable Identifier
R-HSA-9817983
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by CSF1 (M-CSF) in myeloid cells (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds CBL (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The ubiquitin E3 ligase CBL associates with the phosphorylated CSF1R.
Participants
Input
CBL [cytosol]
(Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane]
(Homo sapiens)
Output
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:CBL [plasma membrane]
(Homo sapiens)
Participates
as an event of
Signaling by CSF1 (M-CSF) in myeloid cells (Homo sapiens)
Inferred From
Csf1 dimer:p-Y559-Csf1r dimer:Fyn,Hck,Src,Yes1 binds Cbl (Mus musculus)
Authored
Stanley, ER (2022-10-06)
Created
May, B (2022-10-08)
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