C4b binding protein binds Protein S

Stable Identifier
R-HSA-981665
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
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C4b binding protein binds Protein S
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The beta subunit of C4b binding protein binds and inactivates Protein S, a vitamin K dependent anticoagulation factor. This may represent part of a mechanism for fine-tuning the process of phagocytosis (Kask et al. 2004).

Literature References
PubMed ID Title Journal Year
6454142 High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein

Dahlback, B, Stenflo, J

Proc Natl Acad Sci U S A 1981
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Orthologous Events
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C4b binding protein binds Protein S (Sus scrofa)
C4b binding protein binds Protein S (Xenopus tropicalis)
Authored
Jupe, S  (2010-10-26)
Reviewed
Bradley, DT  (2012-02-13)
Fraczek, LA  (2012-02-13)
Created
Jupe, S  (2010-10-26)