Complement factor I binds C4BP

Stable Identifier
R-HSA-981658
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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C4b-binding protein is a cofactor for Complement Factor I (CFI), allowing it to bind and thereby mediating C4b proteolysis.

Literature References
PubMed ID Title Journal Year
702059 Human C4-binding protein. II. Role in proteolysis of C4b by C3b-inactivator

Fujita, T, Gigli, I, Nussenzweig, V

J Exp Med 1978
293746 Modulation of the classical pathway C3 convertase by plasma proteins C4 binding protein and C3b inactivator

Gigli, I, Fujita, T, Nussenzweig, V

Proc Natl Acad Sci U S A 1979
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