Complement factor I binds C4BP

Stable Identifier
R-HSA-981658
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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C4b-binding protein is a cofactor for Complement Factor I (CFI), allowing it to bind and thereby mediating C4b proteolysis.
Literature References
PubMed ID Title Journal Year
293746 Modulation of the classical pathway C3 convertase by plasma proteins C4 binding protein and C3b inactivator

Gigli, I, Fujita, T, Nussenzweig, V

Proc Natl Acad Sci U S A 1979
702059 Human C4-binding protein. II. Role in proteolysis of C4b by C3b-inactivator

Gigli, I, Fujita, T, Nussenzweig, V

J Exp Med 1978
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