C3b binds to cell surface

Stable Identifier
R-HSA-981539
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Metastable C3b can bind a wide variety of proteins and carbohydrates expressed on biological surfaces (Coico & Sunshine, 2009; Kimball 2010). This is an essentially random event (Dodds & Law, 1998); binding may be to host or microorganism. However, certain surface sugars have greater C3b binding rates, perhaps explaining variations in microorganism suceptibility (Pangburn, M. in The Complement System, Ed. Rother et al. 1998).

Literature References
PubMed ID Title Journal Year
268620 Interaction between the third complement protein and cell surface macromolecules

Law, SK, Levine, RP

Proc Natl Acad Sci U S A 1977
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created