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ST3GAL4 [Golgi membrane]
Stable Identifier
R-HSA-981490
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4, SIA4C_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of protein 3a (Homo sapiens)
O-glycosylation of 3a is terminated (Homo sapiens)
sialyltransferases [Golgi membrane] (Homo sapiens)
ST3GAL4 [Golgi membrane] (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Late SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of protein 3a (Homo sapiens)
O-glycosylation of 3a is terminated (Homo sapiens)
sialyltransferases [Golgi membrane] (Homo sapiens)
ST3GAL4 [Golgi membrane] (Homo sapiens)
Maturation of spike protein (Homo sapiens)
Addition of sialic acids on some Spike glycosyl sidechains (Homo sapiens)
sialyltransferases [Golgi membrane] (Homo sapiens)
ST3GAL4 [Golgi membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Blood group systems biosynthesis (Homo sapiens)
Lewis blood group biosynthesis (Homo sapiens)
ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG (Homo sapiens)
ST3GAL3,4,6 [Golgi membrane] (Homo sapiens)
ST3GAL4 [Golgi membrane] (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Keratan sulfate/keratin metabolism (Homo sapiens)
Keratan sulfate biosynthesis (Homo sapiens)
The keratan chain can be capped by N-acetylneuraminic acid (Homo sapiens)
ST3GAL1-4,6 [Golgi membrane] (Homo sapiens)
ST3GAL4 [Golgi membrane] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
Sialic acid metabolism (Homo sapiens)
ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Homo sapiens)
ST3GAL1-6 [Golgi membrane] (Homo sapiens)
ST3GAL4 [Golgi membrane] (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
N-glycan antennae elongation in the medial/trans-Golgi (Homo sapiens)
N-Glycan antennae elongation (Homo sapiens)
ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Homo sapiens)
ST3GAL4 [Golgi membrane] (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
Termination of O-glycan biosynthesis (Homo sapiens)
ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Homo sapiens)
ST3GAL1-4 [Golgi membrane] (Homo sapiens)
ST3GAL4 [Golgi membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Pre-NOTCH Expression and Processing (Homo sapiens)
Pre-NOTCH Processing in Golgi (Homo sapiens)
Sialylation of Pre-NOTCH (Homo sapiens)
ST3GAL3/4/6 [Golgi membrane] (Homo sapiens)
ST3GAL4 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q11206 ST3GAL4
Gene Names
ST3GAL4, CGS23, NANTA3, SIAT4C, STZ
Chain
chain:1-333
Reference Genes
BioGPS Gene:6484 ST3GAL4
COSMIC (genes):ST3GAL4 ST3GAL4
CTD Gene:6484 ST3GAL4
dbSNP Gene:6484 ST3GAL4
ENSEMBL:ENSG00000110080.20 ST3GAL4
HGNC:10864 ST3GAL4
KEGG Gene (Homo sapiens):6484 ST3GAL4
Monarch:6484 ST3GAL4
NCBI Gene:6484 ST3GAL4
OMIM:104240 ST3GAL4
UCSC:Q11206 ST3GAL4
Reference Transcript
RefSeq:NM_001348399.1 ST3GAL4
RefSeq:NM_001254757.1 ST3GAL4
RefSeq:NM_001348400.1 ST3GAL4
RefSeq:NM_001254759.1 ST3GAL4
RefSeq:NM_006278.2 ST3GAL4
RefSeq:NM_001254758.1 ST3GAL4
Other Identifiers
0005340528
11717813_a_at
11717814_x_at
11754117_a_at
203759_PM_at
203759_at
3355147
3355148
3355149
3355177
3355180
3355181
3355182
3355183
3355184
3355185
3355186
3355187
3355189
3355190
3355193
3355194
3355195
3355197
3355200
3355202
3355203
36916_at
6484
7945110
A_24_P181055
GE59993
GO:0000139
GO:0002376
GO:0003836
GO:0004513
GO:0005575
GO:0005576
GO:0005622
GO:0005794
GO:0005975
GO:0006486
GO:0006629
GO:0006790
GO:0007155
GO:0008118
GO:0008150
GO:0008373
GO:0009101
GO:0009247
GO:0009312
GO:0016020
GO:0016021
GO:0016266
GO:0016740
GO:0016757
GO:0018146
GO:0019082
GO:0030194
GO:0030259
GO:0032580
GO:0036211
GO:0042060
GO:0043226
GO:0047288
GO:0048870
GO:0050877
GO:0050890
GO:0097503
GO:1901135
GO:1903238
GO:1990743
HMNXSV003046842
ILMN_1750086
ILMN_2204545
PH_hs_0004303
TC11001174.hg
X74570_at
g5454057_3p_at
g5454057_3p_x_at
Participates
as a member of
ST3GAL1-4 [Golgi membrane] (Homo sapiens)
ST3GAL3,4,6 [Golgi membrane] (Homo sapiens)
ST3GAL1-4,6 [Golgi membrane] (Homo sapiens)
ST3GAL1-6 [Golgi membrane] (Homo sapiens)
sialyltransferases [Golgi membrane] (Homo sapiens)
as a candidate of
ST3GAL3/4/6 [Golgi membrane] (Homo sapiens)
Inferred To
St3gal4 [Golgi membrane]
(Mus musculus)
St3gal4 [Golgi membrane]
(Rattus norvegicus)
st3gal4 [Golgi membrane]
(Xenopus tropicalis)
C20orf173 [Golgi membrane]
(Gallus gallus)
ST3GAL4 [Golgi membrane]
(Bos taurus)
ST3GAL4 [Golgi membrane]
(Canis familiaris)
ST3GAL4 [Golgi membrane]
(Danio rerio)
ST3GAL4 [Golgi membrane]
(Sus scrofa)
Cross References
RefSeq
NP_006269.1
,
NP_001335329.1
,
NP_001241687.1
,
NP_001335328.1
,
NP_001241686.1
,
NP_001241688.1
OpenTargets
ENSG00000110080
IntEnz
2.4.99.4
GeneCards
Q11206
HPA
ENSG00000110080-ST3GAL4
Ensembl
ENST00000526727
,
ENST00000530591
,
ENST00000532243
,
ENST00000534457
,
ENSP00000436047
,
ENST00000444328
,
ENST00000449406
,
ENSP00000227495
,
ENSP00000433989
,
ENSG00000110080
,
ENSP00000433318
,
ENST00000392669
,
ENST00000227495
,
ENSP00000394354
,
ENSP00000376437
,
ENST00000534083
,
ENSP00000434349
,
ENSP00000399444
,
ENSP00000434668
PRO
Q11206
Pharos - Targets
Q11206
HMDB Protein
HMDBP03118
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