AcK-NFE2L2 binds the NOTCH1 gene

Stable Identifier
R-HSA-9796064
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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AcK-NFE2L2 binds the NOTCH1 gene
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NFE2L2 appears to directly affect Notch1 expression in MEFs and this is likely mediated by the binding of NFE2L2 to a regulatory domain(s) in the −1640 proximal promoter of Notch1 (Wakabayashi et al, 2010; Kim et al, 2014).
Literature References
PubMed ID Title Journal Year
20628156 Regulation of notch1 signaling by nrf2: implications for tissue regeneration

Wakabayashi, J, Yamamoto, M, Slocum, SL, Shin, S, Wakabayashi, N, Kwak, MK, Misra, V, Biswal, S, Kensler, TW, Agoston, ES

Sci Signal 2010
24463449 NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation

Margolick, J, Kim, JH, Matsui, W, Cui, W, Malhotra, SV, Kombairaju, P, Biswal, S, Zhang, H, Thimmulappa, RK, Macvittie, T, Kumar, S, Kumar, V

J Clin Invest 2014
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Authored
Tiwari, K  (2023-08-08)
Created
Tiwari, K  (2022-08-04)
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