NFE2L2 dependent NFE2L2 expression

Stable Identifier
R-HSA-9796060
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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NFE2L2 dependent NFE2L2 expression
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NFE2L2 regulates its own expression thus forming a self-regulatory loop that helps to build up the NFE2L2 response in stress conditions and provides protective support (Kwak et al, 2002)
Literature References
PubMed ID Title Journal Year
22581777 Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha

Kleeberger, SR, Wang, X, Pi, J, Chorley, BN, Campbell, MR, Xue, P, Karaca, M, Sambandan, D, Bangura, F, Bell, DA

Nucleic Acids Res 2012
11940647 Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter

Yamamoto, M, Itoh, K, Kwak, MK, Kensler, TW

Mol Cell Biol 2002
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NFE2L2 gene:p-AcK-NFE2L2:CREBBP,EP300:MAFK [nucleoplasm] (Homo sapiens)
Active Unit
p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm]
Authored
Tiwari, K  (2023-08-08)
Created
Tiwari, K  (2022-08-04)
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