NFE2L2 dependent AREG expression

Stable Identifier
R-HSA-9796057
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
3/5
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The knockdown of NFE2L2 and KEAP1 via short hairpin RNA in BEAS-2B cells and an EMSA with lung tissue revealed that AREG is regulated by NFE2L2. AREG (Amphiregulin) plays role in EGFR signalling (Reiss et al, 2014)
Literature References
PubMed ID Title Journal Year
24921206 Interplay between nuclear factor erythroid 2-related factor 2 and amphiregulin during mechanical ventilation

Uhlig, S, Kan, YW, Parker, M, Siegl, S, Martin, C, Pufe, T, Nautiyal, J, Wruck, CJ, Platen, C, Uhlig, U, Reiss, LK, Fragoulis, A

Am J Respir Cell Mol Biol 2014
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