NFE2L2 dependent BCL2 expression

Stable Identifier
R-HSA-9796055
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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NFE2L2 dependent BCL2 expression
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NFE2L2 upregulates BCL2 expression and apoptotic cell death with implications in antioxidant protection, survival of cancer cells, and drug resistance. (Niture et al 2012)
Literature References
PubMed ID Title Journal Year
22275372 Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis

Niture, SK, Jaiswal, AK

J Biol Chem 2012
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NFE2L2:BCL2 gene complex [nucleoplasm] (Homo sapiens)
Active Unit
p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm]
Authored
Tiwari, K  (2023-08-08)
Created
Tiwari, K  (2022-08-04)
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