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NFkB dependent NFE2L2 expression
Stable Identifier
R-HSA-9796046
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
Nuclear events mediated by NFE2L2 (Homo sapiens)
Regulation of NFE2L2 gene expression (Homo sapiens)
NFkB dependent NFE2L2 expression (Homo sapiens)
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High NFE2L2 expression in human AML is driven by NF-kB (Rushworth et al, 2012).
Literature References
PubMed ID
Title
Journal
Year
23077289
The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance
Zaitseva, L
,
Murray, MY
,
Rushworth, SA
,
MacEwan, DJ
,
Bowles, KM
,
Shah, NM
Blood
2012
Participants
Input
NFE2L2 gene [nucleoplasm]
(Homo sapiens)
Output
NFE2L2 [cytosol]
(Homo sapiens)
Participates
as an event of
Regulation of NFE2L2 gene expression (Homo sapiens)
This event is regulated
Positively by
Regulator
NFE2L2 gene:NFkB complex [nucleoplasm]
(Homo sapiens)
Authored
Tiwari, K (2023-08-08)
Created
Tiwari, K (2022-08-04)
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