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NFE2L2 dependent EGF expression
Stable Identifier
R-HSA-9796044
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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KEAP1-NFE2L2 pathway (Homo sapiens)
Nuclear events mediated by NFE2L2 (Homo sapiens)
NFE2L2 regulating tumorigenic genes (Homo sapiens)
NFE2L2 dependent EGF expression (Homo sapiens)
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NFE2L2 regulating EGFR signalling in Melanoma cells by inducing EGF expression (Kreb et al, 2021)
Literature References
PubMed ID
Title
Journal
Year
33916908
NRF2 Enables EGFR Signaling in Melanoma Cells
Kreß, JKC
,
Meierjohann, S
,
Hufnagel, A
,
Marquardt, A
,
Jessen, C
Int J Mol Sci
2021
Participants
Input
EGF gene [nucleoplasm]
(Homo sapiens)
Output
EGF [extracellular region]
(Homo sapiens)
Participates
as an event of
NFE2L2 regulating tumorigenic genes (Homo sapiens)
This event is regulated
Positively by
Regulator
NFE2L2:EGF gene complex [nucleoplasm]
(Homo sapiens)
Active Unit
p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm]
Authored
Tiwari, K (2023-08-08)
Created
Tiwari, K (2022-08-04)
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