K63PolyUb-K50,p-T357,S358-MLKL [cytosol]

Stable Identifier
R-HSA-9793468
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Icon
K63PolyUb-K50,p-T357,S358-MLKL [cytosol] icon
K63PolyUb-K50,p-T357,S358-MLKL [cytosol] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:Q8NB16 MLKL
Gene Names
MLKL
Chain
chain:1-471
Reference Genes
COSMIC (genes):MLKL MLKL
ENSEMBL:ENSG00000168404 MLKL
HGNC:26617 MLKL
UCSC:Q8NB16 MLKL
Participates
as a component of
Other forms of this molecule
p-T357,S358-MLKL [cytosol]
MLKL [cytosol]
Inferred To
phospho-MLKL [cytosol] (Bos taurus)
phospho-MLKL [cytosol] (Sus scrofa)
phospho-Mlkl [cytosol] (Mus musculus)
phospho-Mlkl [cytosol] (Rattus norvegicus)
Modified Residues
Name
O-phospho-L-serine at 358
Coordinate
358
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 357
Coordinate
357
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 50
Coordinate
50
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
Guide to Pharmacology - Targets
ENSEMBL
OpenTargets
HPA
PRO
Pharos - Targets
GlyGen
HMDB Protein
Interactors (2)
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