Expression of MSGN1 in paraxial mesoderm

Stable Identifier
R-HSA-9793375
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Expression of MSGN1 in paraxial mesoderm
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TBX6 and LEF1:CTNNB1 (LEF1:beta-catenin) bound to the MSGN1 promoter act synergistically to promote transcription of MSGN1 (inferred from mouse homologs). MSGN1 is expressed in unsegmented paraxial mesoderm but expression ceases in nascent somites (Xi et al. 2017 and inferred from mouse homologs).
Literature References
PubMed ID Title Journal Year
28178531 In Vivo Human Somitogenesis Guides Somite Development from hPSCs

Liebscher, S, Xi, H, Schenke-Layland, K, Gonzalez, K, Fujiwara, W, Pyle, AD, Van Handel, B, Jan, M

Cell Rep 2017
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
CTNNB1:LEF1:TBX6:MSGN1 gene [nucleoplasm] (Homo sapiens)
Inferred From
Expression of Msgn1 in paraxial mesoderm (Mus musculus)
Authored
May, B  (2022-06-10)
Reviewed
Chalamalasetty, RB  (2022-11-09)
Yamaguchi, TP  (2022-11-09)
Created
May, B  (2022-06-12)
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