Reactome | KCNQ4 [plasma membrane]

KCNQ4 [plasma membrane]

Stable Identifier

R-HSA-977515

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Potassium voltage-gated channel subfamily KQT member 4, KCNQ4_HUMAN

Locations in the PathwayBrowser

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Neuronal System (Homo sapiens)

- Potassium Channels (Homo sapiens)
  - Voltage gated Potassium channels (Homo sapiens)
    - Activation of voltage gated Potassium channels (Homo sapiens)
      - Octamer of Voltage gated K+ channels [plasma membrane] (Homo sapiens)
        
        Voltage gated potassium channel subunits Kv1-12 [plasma membrane] (Homo sapiens)
        
        Kv7 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)
        
        KCNQ4 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P56696 KCNQ4

Gene Names

KCNQ4

Chain

chain:1-695

Reference Genes

BioGPS Gene:9132 KCNQ4

COSMIC (genes):KCNQ4 KCNQ4

CTD Gene:9132 KCNQ4

dbSNP Gene:9132 KCNQ4

ENSEMBL:ENSG00000117013 KCNQ4

HGNC:6298 KCNQ4

KEGG:hsa:9132 KCNQ4

Monarch:9132 KCNQ4

NCBI Gene:9132 KCNQ4

OMIM:603537 KCNQ4

UCSC:P56696 KCNQ4

Reference Transcript

Other Identifiers

11737015_a_at

11759231_at

16663133

221083_PM_at

221083_at

2332092

2332093

2332094

2332100

2332101

2332102

2332103

2332104

2332105

2332108

2332109

2332110

2332111

2332112

2332113

2332114

2332115

2332116

2332117

2332118

2332119

2332120

2332121

2332122

2332123

243209_PM_at

243209_at

7900492

84163_at

9132

A_23_P34424

GE79219

GO:0005216

GO:0005249

GO:0005267

GO:0005515

GO:0005886

GO:0006811

GO:0006813

GO:0007605

GO:0008076

GO:0009925

GO:0016020

GO:0034220

GO:0034702

GO:0042472

GO:0050877

GO:0055085

GO:0071805

HMNXSV003001332

Hs.161348.0.A1_3p_at

ILMN_1770014

ILMN_2298683

ILMN_2415447

PH_hs_0012933

TC01000518.hg

g4758631_3p_at

Participates

as a component of

KCNQ4 tetramer [plasma membrane] (Homo sapiens)

as a member of

Kv7 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)

Inferred To

KCNQ4 [plasma membrane] (Bos taurus)

KCNQ4 [plasma membrane] (Canis familiaris)

KCNQ4 [plasma membrane] (Gallus gallus)

KCNQ4 [plasma membrane] (Sus scrofa)

Kcnq4 [plasma membrane] (Mus musculus)

kcnq4 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_751895.1, NP_004691.2

Guide to Pharmacology - Targets

563

ENSEMBL

ENST00000347132, ENST00000509682, ENSG00000117013, ENSP00000262916, ENSP00000423756

OpenTargets

ENSG00000117013

ZINC - Substances

KCNQ4_HUMAN

ZINC target

P56696

PRO

P56696

PDB

7BYM, 6N5W, 7BYL, 4GOW, 2OVC, 7VNQ, 7VNR, 7VNP, 7BYN

GeneCards

KCNQ4

HPA

ENSG00000117013-KCNQ4

Pharos - Targets

P56696

Orphanet

KCNQ4

ZINC - Predictions - Purchasable

KCNQ4_HUMAN

HMDB Protein

HMDBP10849

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