Reactome | KCNV2 [plasma membrane]

KCNV2 [plasma membrane]

Stable Identifier

R-HSA-977505

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Potassium voltage-gated channel subfamily V member 2, KCNV2_HUMAN

Locations in the PathwayBrowser

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Neuronal System (Homo sapiens)

- Potassium Channels (Homo sapiens)
  - Voltage gated Potassium channels (Homo sapiens)
    - Activation of voltage gated Potassium channels (Homo sapiens)
      - Octamer of Voltage gated K+ channels [plasma membrane] (Homo sapiens)
        
        Voltage gated potassium channel subunits Kv1-12 [plasma membrane] (Homo sapiens)
        
        Kv8 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)
        
        KCNV2 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8TDN2 KCNV2

Gene Names

KCNV2

Chain

chain:1-545

Reference Genes

BioGPS Gene:169522 KCNV2

COSMIC (genes):KCNV2 KCNV2

CTD Gene:169522 KCNV2

dbSNP Gene:169522 KCNV2

ENSEMBL:ENSG00000168263 KCNV2

HGNC:19698 KCNV2

Monarch:169522 KCNV2

NCBI Gene:169522 KCNV2

OMIM:607604 KCNV2

UCSC:Q8TDN2 KCNV2

Reference Transcript

RefSeq:NM_133497.3 KCNV2

Other Identifiers

11747826_s_at

11759409_at

11759410_s_at

169522

17083221

217522_PM_at

217522_at

3160230

3160231

3160232

3160233

3160234

3160238

3160239

3160240

3160241

3160242

36339_at

8154124

A_23_P32083

GE88437

GO:0001508

GO:0005215

GO:0005216

GO:0005249

GO:0005267

GO:0005515

GO:0005886

GO:0006811

GO:0006813

GO:0008076

GO:0016020

GO:0034702

GO:0051260

GO:0055085

GO:0065003

GO:0071805

HMNXSV003002432

Hs.154131.0.A1_3p_at

PH_hs_0025838

TC09000016.hg

Participates

as a member of

Kv8 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)

Inferred To

kcnv2 [plasma membrane] (Xenopus tropicalis)

Shab [plasma membrane] (Drosophila melanogaster)

Kcnv2 [plasma membrane] (Mus musculus)

Kcnv2 [plasma membrane] (Rattus norvegicus)

KCNV2 [plasma membrane] (Bos taurus)

KCNV2 [plasma membrane] (Canis familiaris)

KCNV2 [plasma membrane] (Gallus gallus)

KCNV2 [plasma membrane] (Sus scrofa)

Cross References

Guide to Pharmacology - Targets

566

ENSEMBL

ENSP00000371514, ENST00000382082

OpenTargets

ENSG00000168263

HPA

ENSG00000168263-KCNV2

PRO

Q8TDN2

Pharos - Targets

Q8TDN2

GlyGen

Q8TDN2

Orphanet

KCNV2

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2

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