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HCN4 [plasma membrane]
Stable Identifier
R-HSA-977498
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, HCN4_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Potassium Channels (Homo sapiens)
HCN channels (Homo sapiens)
Activation of HCN channels (Homo sapiens)
HCNs:cAMP [plasma membrane] (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunit HCN4 [plasma membrane] (Homo sapiens)
HCN4 [plasma membrane] (Homo sapiens)
Binding of cAMP to HCN channels (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunit HCN4 [plasma membrane] (Homo sapiens)
HCN4 [plasma membrane] (Homo sapiens)
HCNs:cAMP [plasma membrane] (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunit HCN4 [plasma membrane] (Homo sapiens)
HCN4 [plasma membrane] (Homo sapiens)
HCNs:cAMP bind SNIs (Homo sapiens)
HCNs:cAMP [plasma membrane] (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunit HCN4 [plasma membrane] (Homo sapiens)
HCN4 [plasma membrane] (Homo sapiens)
HCNs:cAMP:SNIs [plasma membrane] (Homo sapiens)
HCNs:cAMP [plasma membrane] (Homo sapiens)
HCNs [plasma membrane] (Homo sapiens)
HCN channel Homomer of subunit HCN4 [plasma membrane] (Homo sapiens)
HCN4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y3Q4 HCN4
Gene Names
HCN4
Chain
chain:1-1203
Reference Genes
BioGPS Gene:10021 HCN4
COSMIC (genes):HCN4 HCN4
CTD Gene:10021 HCN4
dbSNP Gene:10021 HCN4
ENSEMBL:ENSG00000138622 HCN4
HGNC:16882 HCN4
Monarch:10021 HCN4
NCBI Gene:10021 HCN4
OMIM:605206 HCN4
UCSC:Q9Y3Q4 HCN4
Reference Transcript
RefSeq:NM_005477.2 HCN4
Other Identifiers
10021
11724457_at
11724458_at
16811489
206946_PM_at
206946_at
230208_PM_at
230208_at
32920_at
3632428
3632429
3632430
3632431
3632432
3632433
3632434
3632436
3632438
3632439
3632441
3632447
3632455
3632456
3632457
3632458
3632459
3632460
3632461
3632462
3632463
54329_at
7990244
A_24_P279060
A_33_P3418681
A_33_P3418686
GE739780
GE80562
GO:0002027
GO:0003012
GO:0003013
GO:0003163
GO:0003254
GO:0005215
GO:0005216
GO:0005222
GO:0005248
GO:0005249
GO:0005267
GO:0005272
GO:0005515
GO:0005886
GO:0006811
GO:0006812
GO:0006813
GO:0006814
GO:0006936
GO:0008015
GO:0016020
GO:0030424
GO:0030425
GO:0030552
GO:0034702
GO:0035725
GO:0042391
GO:0042802
GO:0048471
GO:0048856
GO:0055085
GO:0055117
GO:0071320
GO:0071321
GO:0071805
GO:0086012
GO:0086015
GO:0086041
GO:0086046
GO:0086091
GO:0098719
GO:0098855
GO:0098909
GO:1990573
HMNXSV003019908
Hs.86941.0.A1_3p_at
ILMN_1790810
PH_hs_0004882
PH_hs_0012603
TC15001633.hg
TC15002618.hg
g4885406_3p_at
Participates
as a component of
HCN channel Homomer of subunit HCN4 [plasma membrane] (Homo sapiens)
Inferred To
HCN4 [plasma membrane]
(Bos taurus)
HCN4 [plasma membrane]
(Canis familiaris)
HCN4 [plasma membrane]
(Mus musculus)
HCN4 [plasma membrane]
(Rattus norvegicus)
HCN4 [plasma membrane]
(Sus scrofa)
Ih [plasma membrane]
(Drosophila melanogaster)
Cross References
ZINC - World Drugs
HCN4_HUMAN
Guide to Pharmacology - Targets
403
ENSEMBL
ENST00000261917
,
ENSP00000261917
OpenTargets
ENSG00000138622
ZINC - FDA approved
HCN4_HUMAN
ZINC - Substances
HCN4_HUMAN
ZINC target
Q9Y3Q4
PRO
Q9Y3Q4
GlyGen
Q9Y3Q4
PDB
3OTF
,
4HBN
,
4KL1
,
6GYN
,
6GYO
,
4NVP
,
2MNG
,
3U11
HPA
ENSG00000138622-HCN4
Pharos - Targets
Q9Y3Q4
Orphanet
HCN4
ZINC - Predictions - Purchasable
HCN4_HUMAN
HMDB Protein
HMDBP08131
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
3',5'-cyclic GMP [ChEBI:16356]
1
cGMP [cytosol]
(R-ALL-30991)
0.683
4
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