Reactome | KCNA10 [plasma membrane]

KCNA10 [plasma membrane]

Stable Identifier

R-HSA-977480

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Potassium voltage-gated channel subfamily A member 10, KCA10_HUMAN

Locations in the PathwayBrowser

Expand all

Neuronal System (Homo sapiens)

- Potassium Channels (Homo sapiens)
  - Voltage gated Potassium channels (Homo sapiens)
    - Activation of voltage gated Potassium channels (Homo sapiens)
      - Octamer of Voltage gated K+ channels [plasma membrane] (Homo sapiens)
        
        Voltage gated potassium channel subunits Kv1-12 [plasma membrane] (Homo sapiens)
        
        Kv1 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)
        
        KCNA10 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q16322 KCNA10

Gene Names

KCNA10

Chain

chain:1-511

Reference Genes

BioGPS Gene:3744 KCNA10

COSMIC (genes):KCNA10 KCNA10

CTD Gene:3744 KCNA10

dbSNP Gene:3744 KCNA10

ENSEMBL:ENSG00000143105 KCNA10

HGNC:6219 KCNA10

KEGG:hsa:3744 KCNA10

Monarch:3744 KCNA10

NCBI Gene:3744 KCNA10

OMIM:602420 KCNA10

UCSC:Q16322 KCNA10

Reference Transcript

RefSeq:NM_005549.2 KCNA10

Other Identifiers

11738649_at

16690735

208560_PM_at

208560_at

2427539

2427540

2427541

3744

7918444

ADDON002897.hg

A_23_P126528

GE80712

GO:0001508

GO:0005215

GO:0005216

GO:0005221

GO:0005249

GO:0005251

GO:0005267

GO:0005515

GO:0005886

GO:0006811

GO:0006813

GO:0008076

GO:0016020

GO:0034702

GO:0051260

GO:0055085

GO:0065003

GO:0071805

HMNXSV003020240

ILMN_1811380

PH_hs_0013163

TC01002974.hg

g5031818_3p_at

Participates

as a member of

Kv1 subunits of voltage gated potassium channels [plasma membrane] (Homo sapiens)

Inferred To

KCNA10 [plasma membrane] (Bos taurus)

KCNA10 [plasma membrane] (Canis familiaris)

KCNA10 [plasma membrane] (Gallus gallus)

KCNA10 [plasma membrane] (Sus scrofa)

Sh [plasma membrane] (Drosophila melanogaster)

Kcna10 [plasma membrane] (Mus musculus)

Kcna10 [plasma membrane] (Rattus norvegicus)

kcna10 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_005540.1

Guide to Pharmacology - Targets

545

ENSEMBL

ENSP00000358786, ENSG00000143105, ENST00000369771

OpenTargets

ENSG00000143105

GeneCards

KCNA10

HPA

ENSG00000143105-KCNA10

PRO

Q16322

Pharos - Targets

Q16322

GlyGen

Q16322

HMDB Protein

HMDBP08140

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UPQ8 DOLK	6	DOLK [endoplasmic reticulum membrane] (R-HSA-449274) DOLK M1I [endoplasmic reticulum membrane] (R-HSA-4755593) DOLK H408D [endoplasmic reticulum membrane] (R-HSA-4755548) DOLK C99S [endoplasmic reticulum membrane] (R-HSA-4755602) DOLK W304C [endoplasmic reticulum membrane] (R-HSA-4755557) DOLK Y441S [endoplasmic reticulum membrane] (R-HSA-4755590)	0.556	5
UniProt:Q96L58 B3GALT6	11	B3GALT6 [Golgi membrane] (R-HSA-913714) B3GALT6 G217S [Golgi membrane] (R-HSA-4420322) B3GALT6 S65G [Golgi membrane] (R-HSA-4420368) B3GALT6 M1? [Golgi membrane] (R-HSA-4420341) B3GALT6 R197Afs81 [Golgi membrane] (R-HSA-4420356) B3GALT6 R232C [Golgi membrane] (R-HSA-4420361) B3GALT6 D156N [Golgi membrane] (R-HSA-4420367) B3GALT6 C300S [Golgi membrane] (R-HSA-4420366) B3GALT6 D118Afs160 [Golgi membrane] (R-HSA-4420334) B3GALT6 D207H [Golgi membrane] (R-HSA-4420350) B3GALT6 P67L [Golgi membrane] (R-HSA-4420348)	0.527	2
UniProt:Q9H902 REEP1	1	REEP1 [endoplasmic reticulum membrane] (R-HSA-8939766)	0.527	2
UniProt:Q9UBQ6 EXTL2	2	EXTL2 [Golgi membrane] (R-HSA-9941007) EXTL2 [endoplasmic reticulum membrane] (R-HSA-8953372)	0.527	2

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