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shuttling SRSFs [nucleoplasm]
Stable Identifier
R-HSA-9770136
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Formation of pre-mRNPs (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
mRNA 3'-end processing (Homo sapiens)
mRNA Polyadenylation (Homo sapiens)
CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS) (Homo sapiens)
Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
CPA complex components dissociate from polyadenylated pre-mRNA (intronic PAS) (Homo sapiens)
Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
CPA complex components dissociate from polyadenylated pre-mRNA (proximal 3'UTR PAS) (Homo sapiens)
Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
CPSF3 cleaves pre-mRNA at distal 3'UTR PAS (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
CPSF3 cleaves pre-mRNA at proximal 3'UTR PAS (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Core CPA complex binds capped pre-mRNA (Homo sapiens)
Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Homo sapiens)
Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
PP1 dephosphorylates RNA Pol II (Homo sapiens)
CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
RBBP6 activates CPSF complex (Homo sapiens)
CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Recruitment of other CPA components to pre-mRNA-bound CPA core (Homo sapiens)
CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
U1 snRNP suppresses CPSF3-mediated pre-mRNA cleavage at intronic PAS (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Homo sapiens)
Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal A complex (Homo sapiens)
Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal E complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C complex containing intron lariat (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal E complex (Homo sapiens)
Spliceosomal E complex [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Homo sapiens)
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
shuttling SRSFs [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
28152302
SR Proteins: Binders, Regulators, and Connectors of RNA
Jeong, S
Mol Cells
2017
Participants
members
SRSF1 [nucleoplasm]
(Homo sapiens)
SRSF10 [nucleoplasm]
(Homo sapiens)
SRSF3 [nucleoplasm]
(Homo sapiens)
SRSF4 [nucleoplasm]
(Homo sapiens)
SRSF6 [nucleoplasm]
(Homo sapiens)
SRSF7 [nucleoplasm]
(Homo sapiens)
Participates
as a member of
Alternative Splicing Factors [nucleoplasm] (Homo sapiens)
Inferred To
shuttling SRSFs [nucleoplasm]
(Bos taurus)
shuttling SRSFs [nucleoplasm]
(Caenorhabditis elegans)
shuttling SRSFs [nucleoplasm]
(Canis familiaris)
shuttling SRSFs [nucleoplasm]
(Danio rerio)
shuttling SRSFs [nucleoplasm]
(Drosophila melanogaster)
shuttling SRSFs [nucleoplasm]
(Gallus gallus)
shuttling SRSFs [nucleoplasm]
(Mus musculus)
shuttling SRSFs [nucleoplasm]
(Rattus norvegicus)
shuttling SRSFs [nucleoplasm]
(Schizosaccharomyces pombe)
shuttling SRSFs [nucleoplasm]
(Sus scrofa)
srsf3 [nucleoplasm]
(Xenopus tropicalis)
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