Reactome | STEEP1 [nucleoplasm]

STEEP1 [nucleoplasm]

Stable Identifier

R-HSA-9769596

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

fullName evidence="6"STING ER exit protein, STEEP_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H5V9 STEEP1

Gene Names

STEEP1, CXorf56

Chain

chain:1-222

Reference Genes

BioGPS Gene:63932 STEEP1

CTD Gene:63932 STEEP1

dbSNP Gene:63932 STEEP1

ENSEMBL:ENSG00000018610 CXorf56

ENSEMBL_homo_sapiens_GENE:ENSG00000018610.15 STEEP1

HGNC:26239 STEEP1

KEGG Gene (Homo sapiens):63932 STEEP1

Monarch:63932 STEEP1

NCBI Gene:63932 STEEP1

OMIM:301012 STEEP1

UCSC:Q9H5V9 STEEP1

Reference Transcript

Other Identifiers

11739108_a_at

17113582

219805_PM_at

219805_at

235442_PM_at

235442_at

3131686

4019418

4019419

4019420

4019421

4019422

4019423

4019424

4019425

4019426

4019427

4019428

4019430

4019431

4019432

4019433

4019434

4019438

4019440

4019442

63932

8174677

8180338

GE85904

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005783

GO:0005813

GO:0005815

GO:0005856

GO:0006886

GO:0006888

GO:0016192

GO:0030674

GO:0032527

GO:0043226

GO:0044297

GO:0060090

GO:0061024

GO:0090158

HMNXSV003046176

Hs.273627.0.A1_3p_at

ILMN_1730630

PH_hs_0013199

TC0X001310.hg

TC0X002206.hg

g11545812_3p_at

Participates

as an input of

Formation of the Spliceosomal C* complex (Homo sapiens)

as a component of

as an output of

Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)

Inferred To

STEEP1 [nucleoplasm] (Bos taurus)

STEEP1 [nucleoplasm] (Caenorhabditis elegans)

STEEP1 [nucleoplasm] (Canis familiaris)

STEEP1 [nucleoplasm] (Gallus gallus)

STEEP1 [nucleoplasm] (Sus scrofa)

Steep1 [nucleoplasm] (Drosophila melanogaster)

Steep1 [nucleoplasm] (Mus musculus)

Steep1 [nucleoplasm] (Rattus norvegicus)

steep1 [nucleoplasm] (Danio rerio)

steep1 [nucleoplasm] (Xenopus tropicalis)

Ghost homologue of STEEP1 [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of STEEP1 [nucleoplasm] (Plasmodium falciparum)

Ghost homologue of STEEP1 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001164041.1, NP_001164040.1, NP_071384.1

OpenTargets

ENSG00000018610

GeneCards

Q9H5V9

HPA

ENSG00000018610-STEEP1

Ensembl

ENSP00000320345, ENSP00000441786, ENST00000536133, ENSP00000494123, ENST00000320339, ENST00000644802, ENSG00000018610

PRO

Q9H5V9

Pharos - Targets

Q9H5V9

Orphanet

27023

PDB

8C6J

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14929 HAT1	1	HAT1 [nucleoplasm] (R-HSA-3662337)	0.556	3
UniProt:Q4G0R1 Q4G0R1			0.556	3
IntAct:EBI-10279280 132954			0.556	3
UniProt:Q9NQG5 RPRD1B	1	RPRD1B [nucleoplasm] (R-HSA-6814894)	0.556	3
UniProt:Q9HAQ2 KIF9	1	KIF9 [cytosol] (R-HSA-984616)	0.556	3
UniProt:Q8N4N3 KLH36			0.527	3
UniProt:Q9Y3E7 CHMP3	2	CHMP3 [cytosol] (R-HSA-917722) CHMP3 [endosome membrane] (R-HSA-9631191)	0.527	2

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