Reactome | PRKRIP1 [nucleoplasm]

PRKRIP1 [nucleoplasm]

Stable Identifier

R-HSA-9769594

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PRKR-interacting protein 1, PKRI1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H875 PRKRIP1

Gene Names

PRKRIP1

Chain

chain:1-184

Reference Genes

BioGPS Gene:79706 PRKRIP1

COSMIC (genes):PRKRIP1 PRKRIP1

CTD Gene:79706 PRKRIP1

dbSNP Gene:79706 PRKRIP1

ENSEMBL:ENSG00000128563 PRKRIP1

HGNC:21894 PRKRIP1

KEGG:hsa:79706 PRKRIP1

Monarch:79706 PRKRIP1

NCBI Gene:79706 PRKRIP1

OMIM:617458 PRKRIP1

UCSC:Q9H875 PRKRIP1

Reference Transcript

RefSeq:NM_024653.3 PRKRIP1

Other Identifiers

11722581_a_at

11722582_a_at

11746807_a_at

11746808_x_at

17049797

218378_PM_s_at

218378_s_at

222615_PM_s_at

222615_s_at

2988472

3007445

3007447

3007452

3007453

3007457

3009582

3009583

3009587

3009588

3016712

3016713

3016714

3016715

3016716

3016717

3016718

3016719

3016721

3016722

3016741

3016742

3016743

3016745

3016747

3016751

3016752

3016753

3016755

3016759

3016760

3057293

3057299

3057300

3057318

3057319

3057331

3057775

3057777

53675_at

62468_at

74655_at

79706

8135162

A_14_P100434

A_23_P82316

A_24_P320759

A_33_P3235925

GE81503

GE87631

GO:0003014

GO:0003723

GO:0003725

GO:0004860

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005730

GO:0006397

GO:0006469

GO:0008380

GO:0016071

GO:0019901

GO:0042326

GO:0043226

GO:0070062

GO:0098772

HMNXSV003028071

HMNXSV003056485

Hs.301862.1.A1_3p_s_at

Hs.58127.0.S1_3p_a_at

ILMN_1699049

ILMN_1804490

PH_hs_0024676

PH_hs_0037605

TC07000658.hg

TC07002502.hg

g13375900_3p_a_at

p33722

Participates

as an input of

Formation of the Spliceosomal C* complex (Homo sapiens)

as a component of

as an output of

Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)

Inferred To

Dmel\CG8441 [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of PRKRIP1 [nucleoplasm] (Schizosaccharomyces pombe)

PRKRIP1 [nucleoplasm] (Bos taurus)

PRKRIP1 [nucleoplasm] (Caenorhabditis elegans)

PRKRIP1 [nucleoplasm] (Canis familiaris)

PRKRIP1 [nucleoplasm] (Dictyostelium discoideum)

PRKRIP1 [nucleoplasm] (Gallus gallus)

PRKRIP1 [nucleoplasm] (Plasmodium falciparum)

PRKRIP1 [nucleoplasm] (Sus scrofa)

prkrip1 [nucleoplasm] (Danio rerio)

prkrip1 [nucleoplasm] (Xenopus tropicalis)

Prkrip1 [nucleoplasm] (Mus musculus)

Prkrip1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_078929.1

ENSEMBL

ENST00000397912, ENSP00000381010, ENST00000496391, ENSP00000419270

OpenTargets

ENSG00000128563

HPA

ENSG00000128563-PRKRIP1

PRO

Q9H875

Pharos - Targets

Q9H875

PDB

7W5B, 8C6J, 7W5A, 6QDV, 5XJC, 6ICZ

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3
UniProt:P63162 SNRPN	1	Me2-R108,R112-SNRPN [nucleoplasm] (R-HSA-8865931)	0.527	2
UniProt:P62304 SNRPE	2	SNRPE [cytosol] (R-HSA-191782) SNRPE [nucleoplasm] (R-HSA-71905)	0.527	2
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.527	3

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