Reactome | CACTIN [nucleoplasm]

CACTIN [nucleoplasm]

Stable Identifier

R-HSA-9769591

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Cactin, CATIN_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WUQ7 CACTIN

Gene Names

CACTIN, C19orf29

Chain

chain:1-758

Reference Genes

BioGPS Gene:58509 CACTIN

COSMIC (genes):CACTIN CACTIN

CTD Gene:58509 CACTIN

dbSNP Gene:58509 CACTIN

ENSEMBL:ENSG00000105298 CACTIN

ENSEMBL_homo_sapiens_GENE:ENSG00000105298.14 CACTIN

HGNC:29938 CACTIN

KEGG Gene (Homo sapiens):58509 CACTIN

Monarch:58509 CACTIN

NCBI Gene:58509 CACTIN

OMIM:618536 CACTIN

UCSC:Q8WUQ7 CACTIN

Reference Transcript

Other Identifiers

11723913_a_at

11723914_x_at

11723915_a_at

11745056_x_at

11750971_a_at

11750972_x_at

16867097

213815_PM_x_at

213815_x_at

214892_PM_x_at

214892_x_at

215954_PM_s_at

215954_s_at

240373_PM_at

240373_at

3057035

32913_i_at

32914_f_at

3846291

3846292

3846293

3846294

3846295

3846296

3846298

3846299

3846301

3846303

3846304

3846307

3846308

3846309

3846310

3846311

3846312

3846313

3846314

3846315

58509

68009_at

8032637

A_23_P372144

A_23_P372151

GE54442

GO:0000398

GO:0001933

GO:0002376

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005737

GO:0005829

GO:0006351

GO:0006355

GO:0006397

GO:0008380

GO:0016071

GO:0016607

GO:0023052

GO:0031665

GO:0032088

GO:0032688

GO:0032717

GO:0032720

GO:0034122

GO:0036211

GO:0043124

GO:0043226

GO:0045087

GO:0045292

GO:0045824

GO:0060339

GO:0071013

GO:0071222

GO:0071347

GO:0071356

GO:0098542

HMNXSV003052430

Hs.128425.0.S1_3p_a_at

Hs.189097.0.A1_3p_at

ILMN_2262462

ILMN_2350421

PH_hs_0018121

TC19001047.hg

Participates

as an input of

Formation of the Spliceosomal C* complex (Homo sapiens)

as a component of

as an output of

Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)

Inferred To

cacn-1 [nucleoplasm] (Caenorhabditis elegans)

CACTIN [nucleoplasm] (Bos taurus)

CACTIN [nucleoplasm] (Canis familiaris)

CACTIN [nucleoplasm] (Dictyostelium discoideum)

CACTIN [nucleoplasm] (Gallus gallus)

CACTIN [nucleoplasm] (Plasmodium falciparum)

CACTIN [nucleoplasm] (Sus scrofa)

cay1 [nucleoplasm] (Schizosaccharomyces pombe)

Cactin [nucleoplasm] (Mus musculus)

Cactin [nucleoplasm] (Rattus norvegicus)

cactin [nucleoplasm] (Danio rerio)

cactin [nucleoplasm] (Drosophila melanogaster)

cactin [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_067054.1, NP_001074012.1

OpenTargets

ENSG00000105298

HPA

ENSG00000105298-CACTIN

GeneCards

Q8WUQ7

Ensembl

ENSP00000415078, ENST00000248420, ENSP00000465751, ENST00000429344, ENST00000585942, ENSP00000221899, ENST00000221899, ENSP00000248420, ENSG00000105298

PRO

Q8WUQ7

Pharos - Targets

Q8WUQ7

PDB

6QDV, 8C6J, 7W5A, 7W5B

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49760 CLK2			0.556	3
UniProt:P67870 CSNK2B	5	CSNK2B [secretory granule lumen] (R-HSA-6801319) CSNK2B [extracellular region] (R-HSA-6806508) CSNK2B [ficolin-1-rich granule lumen] (R-HSA-6801290) CSNK2B [nucleoplasm] (R-HSA-6805067) CSNK2B [cytosol] (R-HSA-201693)	0.527	3