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PPIL2 [nucleoplasm]
Stable Identifier
R-HSA-9769562
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
fullName evidence="12"RING-type E3 ubiquitin-protein ligase PPIL2 ecNumber evidence="4"2.3.2.27/ecNumber, PPIL2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C complex containing intron lariat (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
PPIL2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13356 PPIL2
Gene Names
PPIL2
Chain
chain:1-520
Reference Genes
BioGPS Gene:23759 PPIL2
COSMIC (genes):PPIL2 PPIL2
CTD Gene:23759 PPIL2
dbSNP Gene:23759 PPIL2
ENSEMBL:ENSG00000100023 PPIL2
HGNC:9261 PPIL2
KEGG:hsa:23759 PPIL2
Monarch:23759 PPIL2
NCBI Gene:23759 PPIL2
OMIM:607588 PPIL2
UCSC:Q13356 PPIL2
Reference Transcript
RefSeq:NM_014337.3 PPIL2
RefSeq:NM_001317996.1 PPIL2
RefSeq:XM_005261448.3 PPIL2
RefSeq:XM_011530047.2 PPIL2
RefSeq:NM_148175.2 PPIL2
RefSeq:NM_148176.2 PPIL2
RefSeq:XM_011530046.2 PPIL2
Other Identifiers
11729519_x_at
11739070_x_at
11746953_a_at
11747844_x_at
11752540_s_at
11752541_x_at
11760678_at
11762400_s_at
16927639
206063_3p_x_at
206063_PM_x_at
206063_x_at
206064_PM_s_at
206064_s_at
209299_PM_x_at
209299_x_at
214986_3p_x_at
214986_PM_x_at
214986_x_at
217407_3p_x_at
217407_PM_x_at
217407_x_at
223999_PM_at
223999_at
23759
243414_PM_at
243414_at
33188_at
35448_at
3652081
39111_s_at
3938259
3938260
3938261
3938262
3938263
3938264
3938265
3938266
3938267
3938268
3938269
3938270
3938272
3938273
3938274
3938275
3938276
3938277
3938278
3938279
3938280
3938281
3938282
3938283
3938284
3938285
3938286
3938288
3938289
3938290
3938291
3938292
3938293
3938294
3938295
3938296
3938297
3938298
3938299
3938300
3938301
3938302
3938303
3938304
3938305
3938306
3938307
3938308
3938309
77409_at
8071566
92106_at
A_14_P103693
A_14_P115710
A_23_P432512
A_24_P284783
A_24_P923591
GE62510
GE79902
GO:0000209
GO:0000413
GO:0003755
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005737
GO:0005796
GO:0005886
GO:0006397
GO:0006457
GO:0008380
GO:0016071
GO:0016567
GO:0016740
GO:0016853
GO:0034450
GO:0043226
GO:0061630
GO:0071013
GO:0072659
GO:0140096
HMNXSV003013003
Hs.174159.0.A1_3p_at
Hs.93523.0.A2_3p_a_at
Hs.93523.0.A2_3p_x_at
Hs.93523.3.A1_3p_a_at
Hs.93523.4.A1_3p_a_at
Hs.93523.4.A1_3p_x_at
ILMN_1675273
ILMN_1729690
ILMN_1802872
PH_hs_0026143
TC22000096.hg
U37219_at
U37221_at
g12751383_3p_at
g13366578_3p_a_at
g7657472_3p_a_at
Participates
as an input of
Formation of the Spliceosomal Bact complex (Homo sapiens)
as a component of
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
as an output of
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Other forms of this molecule
PPIL2 [Golgi lumen]
Inferred To
PPIL2 [nucleoplasm]
(Bos taurus)
PPIL2 [nucleoplasm]
(Canis familiaris)
PPIL2 [nucleoplasm]
(Gallus gallus)
PPIL2 [nucleoplasm]
(Sus scrofa)
ppil2 [nucleoplasm]
(Danio rerio)
ppil2 [nucleoplasm]
(Dictyostelium discoideum)
ppil2 [nucleoplasm]
(Xenopus tropicalis)
cyn-4 [nucleoplasm]
(Caenorhabditis elegans)
Ppil2 [nucleoplasm]
(Mus musculus)
Ppil2 [nucleoplasm]
(Rattus norvegicus)
CYC4 [nucleoplasm]
(Drosophila melanogaster)
cyp8 [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of PPIL2 [nucleoplasm]
(Plasmodium falciparum)
Cross References
RefSeq
XP_011528348.1
,
XP_011528349.1
,
NP_680481.1
,
NP_680480.1
,
NP_055152.1
,
NP_001304925.1
,
XP_005261505.1
OpenTargets
ENSG00000100023
ENSEMBL
ENST00000680061
,
ENSP00000506328
,
ENSP00000486725
,
ENST00000679540
,
ENST00000679534
,
ENST00000681956
,
ENSP00000384299
,
ENST00000679795
,
ENSP00000504893
,
ENST00000398831
,
ENSP00000506158
,
ENSP00000506542
,
ENSP00000506144
,
ENSP00000334553
,
ENSP00000505910
,
ENST00000626352
,
ENSP00000381812
,
ENST00000335025
,
ENST00000406385
,
ENST00000680393
HPA
ENSG00000100023-PPIL2
PRO
Q13356
Pharos - Targets
Q13356
GlyGen
Q13356
PDB
7ABI
,
1ZKC
,
8CH6
,
7QTT
,
7DVQ
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96NB3 ZNF830
1
ZNF830 [nucleoplasm]
(R-HSA-6781962)
0.632
3
UniProt:P36406 TRI23
0.556
3
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.527
2
UniProt:Q5QP82 DCAF10
1
DCAF10 [nucleoplasm]
(R-HSA-8955194)
0.499
3
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