Variant fibrinogen alpha chain [extracellular region]

Stable Identifier
R-HSA-976905
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Icon
Variant fibrinogen alpha chain [extracellular region] icon
Variant fibrinogen alpha chain [extracellular region] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
8097946 Hereditary renal amyloidosis associated with a mutant fibrinogen alpha-chain

Benson, MD, Liepnieks, J, Uemichi, T, Wheeler, G, Correa, R

Nat Genet 1993
External Reference Information
External Reference
UniProt:P02671 FGA
Gene Names
FGA
Chain
signal peptide:1-19, peptide:20-35, chain:36-866
Reference Genes
BioGPS Gene:2243 FGA
COSMIC (genes):FGA FGA
CTD Gene:2243 FGA
dbSNP Gene:2243 FGA
ENSEMBL:ENSG00000171560 FGA
HGNC:3661 FGA
KEGG Gene (Homo sapiens):2243 FGA
Monarch:2243 FGA
NCBI Gene:2243 FGA
OMIM:134820 FGA
UCSC:P02671 FGA
Reference Transcript
Other Identifiers
0002360161
0003850594
11749963_a_at
11757349_a_at
11757350_x_at
16776
16980836
1BBR
1DM4
1FPH
1FZA
1FZB
1FZC
1FZD
1FZE
1FZF
1FZG
1LT9
1LTJ
1N86
1N8E
1RE3
1RE4
1RF0
1RF1
1YCP
205650_s_at
2243
2790631
2790632
2790633
2790634
2790635
2790636
2790637
2790638
2790639
2790640
2790641
2790642
2790643
2790644
2790645
2790646
2790647
2790648
2790649
2A45
2FFD
2H43
2HLO
2HOD
2HPC
2OYH
2OYI
2Q9I
2XNX
2XNY
2Z4E
3AT0
3BVH
3E1I
3GHG
3H32
3HUS
4F27
51370
5CFA
8103311
A0A087WUA0
A_23_P375372
AAA17055
AAA17056
AAA52426
AAA52427
AAA52428
AAA52444
AAC97142
AAC97143
AAH98280
AAH99706
AAH99720
AAI01936
AAK31372
AAK31373
AF361104
AK290559
BAF83248
BC098280
BC099706
BC099720
BC101935
CAB016776
CCDS47152
CH471056
EAX04925
EAX04926
EAX04927
EAX04928
ENSG00000171560
ENSP00000385981
ENST00000403106
ENST00000403106.7
EntrezGene:2243
EntrezGene:FGA
FGA
FGA-201
g11761628_3p_s_at
GE79857
GO:0000902
GO:0002224
GO:0002250
GO:0002376
GO:0002576
GO:0003013
GO:0003674
GO:0005102
GO:0005198
GO:0005201
GO:0005515
GO:0005575
GO:0005576
GO:0005577
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005783
GO:0005788
GO:0005886
GO:0006464
GO:0006810
GO:0006950
GO:0007155
GO:0007160
GO:0007165
GO:0007267
GO:0007596
GO:0007599
GO:0008150
GO:0008219
GO:0009897
GO:0009986
GO:0016192
GO:0022607
GO:0030154
GO:0030168
GO:0030198
GO:0031012
GO:0031091
GO:0031093
GO:0031410
GO:0031639
GO:0032991
GO:0034116
GO:0034622
GO:0042730
GO:0043152
GO:0043167
GO:0043226
GO:0043687
GO:0044267
GO:0045087
GO:0045907
GO:0045921
GO:0046872
GO:0048856
GO:0050714
GO:0050839
GO:0051258
GO:0051592
GO:0051604
GO:0062023
GO:0065003
GO:0070062
GO:0070374
GO:0070527
GO:0072377
GO:0072378
GO:0072562
GO:0090277
GO:1900026
GO:1902042
GO:1903561
GO:2000352
HGNC:3661
HPA051370
HPA064755
ILMN_1656487
ILMN_1779017
ILMN_2381945
IPR012290
IPR021996
J00127
J00128
K02272
LRG_557
M26878
M58569
M64982
MIM:105200
MIM:134820
MIM:202400
MIM:616004
NM_021871
NP_068657
PF08702
PF12160
PH_hs_0028209
SM01212
TC04001662.hg
TC04002793.hg
UPI000002A9B1
Participant Of
hasMember
repeatedUnit
Other forms of this molecule
FGA(20-866) [extracellular region]
FGA(20-866) [platelet alpha granule lumen]
FGA(20-35) [extracellular region]
p-FGA [endoplasmic reticulum lumen]
FGA [endoplasmic reticulum lumen]
FGA [plasma membrane]
FGA [extracellular region]
Modified Residues
Name
L-leucine residue 573 replaced with unknown
Coordinate
573
PsiMod
L-leucine residue [MOD:00020]
A protein modification that effectively converts a source amino acid residue to an L-leucine.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
PDB
Interactors (5)