NPAS4 binds FOS gene enhancer

Stable Identifier
R-HSA-9768950
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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NPAS4 binds FOS gene enhancer
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Based on a study conducted using mouse cortical and hippocampal neurons as the model system, NPAS4 binds an enhancer element of the FOS gene (Kim et al. 2010; Ramamoorthi et al. 2011). In rat primary neurons, Npas4 and its heterodimerization partners Arnt and Arnt2 were shown to bind multiple sites in the Fos gene locus by high-throughput ChIP-seq (Brigidi et al. 2019). The heterodimers of NPAS4 with ARNT, ARNT2 and ARNTL are annotated as candidates for Fos gene binding.
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Npas4 binds Fos gene enhancer (Mus musculus)
Authored
Orlic-Milacic, M  (2022-04-08)
Reviewed
Lin, Y  (2022-07-29)
Created
Orlic-Milacic, M  (2022-03-15)
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