NPAS4 stimulates FOS gene expression

Stable Identifier
R-HSA-9768945
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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NPAS4 stimulates FOS gene expression
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Based on a study conducted using mouse hippocampal neurons as the model system, NPAS4 directly stimulates FOS gene transcription (Ramamoorthi et al. 2011). In rat primary neurons, Fos gene transcription is significantly upregulated upon Npas4 activation (Brigidi et al. 2019).
Participants
Input
Output
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as an event of
This event is regulated
Positively by
Regulator
(NPAS4:ARNTL,NPAS4:ARNT,NPAS4:ARNT2):FOS gene [nucleoplasm] (Homo sapiens)
Active Unit
(NPAS4:ARNTL,NPAS4:ARNT,NPAS4:ARNT2) [nucleoplasm]
Inferred From
Npas4 stimulates Fos gene transcription (Mus musculus)
Authored
Orlic-Milacic, M  (2022-04-08)
Reviewed
Lin, Y  (2022-07-29)
Created
Orlic-Milacic, M  (2022-03-15)
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