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APOA4(21-94) [extracellular region]
Stable Identifier
R-HSA-976882
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Apolipoprotein A-IV amyloid fragment, APOA4, APOA4_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Amyloid fiber formation (Homo sapiens)
Amyloid fibrils have additional components (Homo sapiens)
Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Systemic amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Apolipoprotein A-IV fibril [extracellular region] (Homo sapiens)
APOA4(21-94) [extracellular region] (Homo sapiens)
Amyloid fibrils [plasma membrane] (Homo sapiens)
Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Systemic amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Apolipoprotein A-IV fibril [extracellular region] (Homo sapiens)
APOA4(21-94) [extracellular region] (Homo sapiens)
Amyloid precursor proteins form ordered fibrils (Homo sapiens)
Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Systemic amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
Apolipoprotein A-IV fibril [extracellular region] (Homo sapiens)
APOA4(21-94) [extracellular region] (Homo sapiens)
Amyloid fibril monomers [extracellular region] (Homo sapiens)
Systemic amyloid fibril monomers [extracellular region] (Homo sapiens)
APOA4(21-94) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P06727 APOA4
Gene Names
APOA4
Chain
signal peptide:1-20, chain:21-396
Reference Genes
BioGPS Gene:337 APOA4
COSMIC (genes):APOA4 APOA4
CTD Gene:337 APOA4
dbSNP Gene:337 APOA4
ENSEMBL:ENSG00000110244 APOA4
HGNC:602 APOA4
KEGG Gene (Homo sapiens):337 APOA4
Monarch:337 APOA4
NCBI Gene:337 APOA4
OMIM:107690 APOA4
UCSC:P06727 APOA4
Reference Transcript
RefSeq:NM_000482.3 APOA4
Other Identifiers
0000770022
11758243_s_at
16744717
206894_at
337
3392975
3392976
3392977
3392978
3392979
3392980
3392981
3392983
3392984
3392985
34523_at
7951859
8077192
A_23_P87036
A_24_P252934
GO:0001523
GO:0002227
GO:0002376
GO:0003674
GO:0005319
GO:0005507
GO:0005515
GO:0005543
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005768
GO:0005769
GO:0005783
GO:0005788
GO:0005829
GO:0006629
GO:0006695
GO:0006810
GO:0006869
GO:0006950
GO:0006982
GO:0007155
GO:0007159
GO:0008150
GO:0008203
GO:0008289
GO:0009056
GO:0009058
GO:0009986
GO:0010873
GO:0010898
GO:0015485
GO:0016042
GO:0016209
GO:0019430
GO:0022607
GO:0030234
GO:0030300
GO:0031012
GO:0031210
GO:0031410
GO:0032374
GO:0032991
GO:0033344
GO:0033700
GO:0034361
GO:0034364
GO:0034371
GO:0034372
GO:0034375
GO:0034378
GO:0034380
GO:0034445
GO:0035634
GO:0042157
GO:0042592
GO:0042627
GO:0042632
GO:0042744
GO:0042802
GO:0042803
GO:0043167
GO:0043226
GO:0043691
GO:0044281
GO:0045723
GO:0046470
GO:0046889
GO:0051006
GO:0055088
GO:0060228
GO:0061024
GO:0062023
GO:0065003
GO:0065005
GO:0070062
GO:0070328
GO:0072562
GO:0120009
GO:0120020
GO:1990000
HMNXSV003031882
ILMN_1675706
J02758_s_at
PH_hs_0030866
TC11002327.hg
g5174773_3p_at
g5174773_3p_x_at
Participates
as a member of
Systemic amyloid fibril monomers [extracellular region] (Homo sapiens)
as a repeated unit of
Apolipoprotein A-IV fibril [extracellular region] (Homo sapiens)
Other forms of this molecule
APOA4 [endoplasmic reticulum lumen]
APOA4 [cytosol]
APOA4 [extracellular region]
APOA4 [early endosome]
Cross References
RefSeq
NP_000473.2
OpenTargets
ENSG00000110244
GeneCards
P06727
HPA
ENSG00000110244-APOA4
Ensembl
ENST00000357780
,
ENSP00000350425
,
ENSG00000110244
PRO
P06727
Pharos - Targets
P06727
GlyGen
P06727
Orphanet
24347
PDB
3S84
HMDB Protein
HMDBP02093
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06727 APOA4
5
APOA4(21-94) [extracellular region]
(R-HSA-976882)
APOA4 [endoplasmic reticulum lumen]
(R-HSA-174667)
APOA4 [cytosol]
(R-HSA-2395773)
APOA4 [extracellular region]
(R-HSA-174701)
APOA4 [early endosome]
(R-HSA-2429647)
0.678
10
UniProt:Q96DZ9-2 CMTM5
0.556
3
UniProt:P43360 MAGA6
0.556
3
UniProt:Q9Y371 SHLB1
0.556
3
UniProt:Q8IZR5-2 Q8IZR52
0.556
3
UniProt:Q6RW13-2 AGTRAP
0.556
3
UniProt:P55212 CASP6
5
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(194-293) [cytosol]
(R-HSA-266128)
0.556
3
UniProt:P20393 NR1D1
1
NR1D1 [nucleoplasm]
(R-HSA-375499)
0.518
3
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