TCF12 binds CDH1 gene promoter

Stable Identifier
R-HSA-9767922
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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TCF12 binds CDH1 gene promoter
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TCF12 (also known as HEB, BHLHB20 or HTF4) binds to the CDH1 (E-cadherin) gene promoter (Li et al. 2007; Lee et al. 2012).
Literature References
PubMed ID Title Journal Year
22130667 TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancer

Lee, CC, Chen, WS, Chen, CC, Chen, LL, Lin, YS, Fan, CS, Huang, TS

J Biol Chem 2012
17202424 Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor Id1

Li, Y, Yang, J, Luo, JH, Dedhar, S, Liu, Y

J Am Soc Nephrol 2007
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Authored
Orlic-Milacic, M  (2022-03-02)
Created
Orlic-Milacic, M  (2022-03-02)
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