Serum amyloid P-component forms homopentamers

Stable Identifier
R-HSA-976723
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Serum amyloid P component (SAP) is a member of the pentraxin family, characterized by the formation of pentameric ring structures. Each member of the ring has two associated calcium ions. SAP is an acute phase reactant, highly induced by IL-6. It has 50% homology with the related C-reactive peptide.

Literature References
PubMed ID Title Journal Year
8114934 Structure of pentameric human serum amyloid P component

Emsley, J, White, HE, O'Hara, BP, Oliva, G, Srinivasan, N, Tickle, IJ, Blundell, TL, Pepys, MB, Wood, SP

Nature 1994
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