GSK3-dependent phosphorylation of NFE2L2 promotes its subsequent ubiquitination by a BTRC:CUL1 E3 ligase complex (Salazar et al, 2006; Rada et al, 2011; Rada et al, 2012; Rojo et al, 2012; reviewed in Baird and Yamamoto, 2020; Yamamoto et al, 2018).
Motohashi, H, Yamamoto, M, Kensler, TW
Cuadrado, A, Chowdhry, S, Rojo, AI, Rada, P, Hayes, JD, McMahon, M
Yamamoto, M, Baird, L
Rada, P, Garcia-Mayoral, MF, Cotte, A, Innamorato, NG, Van Leuven, F, Cuadrado, A, Devijver, H, Rojo, AI, Evrard-Todeschi, N, Hayes, JD, Tobón-Velasco, JC, Jaworski, T, Bertho, G
de Sagarra, RM, Velasco, D, Cuadrado, A, Salazar, M, Rojo, AI
Cuadrado, A, Medina-Campos, ON, Pedraza-Chaverri, J, Rojo, AI, Rada, P, Zúñiga-Toalá, A, Espada, S, López-Gazcón, A
ubiquitin protein ligase activity of BTRC:SKP1:CUL1:RBX1:p-S335, S338 NFE2L2 [nucleoplasm]
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