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TRIM36 [cytosol]
Stable Identifier
R-HSA-976029
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase TRIM36, TRI36_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM36 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NQ86 TRIM36
Gene Names
TRIM36, RBCC728, RNF98
Chain
chain:1-728
Reference Genes
BioGPS Gene:55521 TRIM36
COSMIC (genes):TRIM36 TRIM36
CTD Gene:55521 TRIM36
dbSNP Gene:55521 TRIM36
ENSEMBL:ENSG00000152503 TRIM36
ENSEMBL_homo_sapiens_GENE:ENSG00000152503.10 TRIM36
HGNC:16280 TRIM36
KEGG Gene (Homo sapiens):55521 TRIM36
Monarch:55521 TRIM36
NCBI Gene:55521 TRIM36
OMIM:609317 TRIM36
UCSC:Q9NQ86 TRIM36
Reference Transcript
RefSeq:NM_018700.3 TRIM36
RefSeq:NM_001300759.1 TRIM36
RefSeq:NM_001017398.1 TRIM36
RefSeq:NM_001017397.1 TRIM36
RefSeq:NM_001300752.1 TRIM36
Other Identifiers
11726237_at
11726238_s_at
11731961_s_at
11736582_a_at
11736583_a_at
219736_PM_at
219736_at
231123_PM_at
231123_at
2871618
2871619
2871620
2871621
2871622
2871624
2871625
2871626
2871627
2871629
2871636
2871637
2871638
2871641
2871642
2871643
2871644
2871645
2871646
2871653
2871654
45502_at
55226_at
55521
57017_at
76295_at
8113577
A_23_P110569
A_24_P363134
A_33_P3390793
GE62613
GO:0000278
GO:0000281
GO:0000910
GO:0001669
GO:0003824
GO:0004842
GO:0005515
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0007010
GO:0007051
GO:0007340
GO:0008092
GO:0008270
GO:0016740
GO:0022414
GO:0031410
GO:0036211
GO:0043014
GO:0043226
GO:0046872
GO:0051726
GO:0070507
GO:0140096
HMNXSV003028539
HMNXSV003058236
Hs.112644.0.S1_3p_at
Hs2.405967.1.A1_3p_s_at
ILMN_1668453
ILMN_1674580
ILMN_1724350
ILMN_2361737
PH_hs_0040413
TC05001684.hg
g8924237_3p_at
Participates
as a member of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
madd-2 [cytosol]
(Caenorhabditis elegans)
trim36 [cytosol]
(Xenopus tropicalis)
TRIM36 [cytosol]
(Bos taurus)
TRIM36 [cytosol]
(Canis familiaris)
TRIM36 [cytosol]
(Drosophila melanogaster)
TRIM36 [cytosol]
(Gallus gallus)
TRIM36 [cytosol]
(Mus musculus)
TRIM36 [cytosol]
(Sus scrofa)
wu:fj48f01 [cytosol]
(Danio rerio)
Trim36 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_061170.2
,
NP_001017397.1
,
NP_001017398.1
,
NP_001287681.1
,
NP_001287688.1
OpenTargets
ENSG00000152503
HPA
ENSG00000152503-TRIM36
GeneCards
Q9NQ86
Ensembl
ENSP00000423934
,
ENST00000282369
,
ENSG00000152503
,
ENST00000379618
,
ENST00000379617
,
ENSP00000368938
,
ENSP00000368937
,
ENST00000513154
,
ENSP00000282369
PRO
Q9NQ86
Pharos - Targets
Q9NQ86
PDB
7QS4
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O76003 GLRX3
1
GLRX3 [cytosol]
(R-HSA-5691202)
0.718
6
UniProt:Q9Y297 BTRC
2
BTRC [cytosol]
(R-HSA-174237)
BTRC [nucleoplasm]
(R-HSA-3361753)
0.556
3
UniProt:Q96NC0 ZMAT2
1
ZMAT2 [nucleoplasm]
(R-HSA-9770248)
0.556
3
UniProt:Q14451 GRB7
1
GRB7 [cytosol]
(R-HSA-204819)
0.556
3
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