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RNF144B [cytosol]
Stable Identifier
R-HSA-975988
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase RNF144B, R144B_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF144B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z419 RNF144B
Gene Names
RNF144B, IBRDC2, P53RFP
Chain
chain:1-303
Reference Genes
BioGPS Gene:255488 RNF144B
COSMIC (genes):RNF144B RNF144B
CTD Gene:255488 RNF144B
dbSNP Gene:255488 RNF144B
ENSEMBL:ENSG00000137393 RNF144B
HGNC:21578 RNF144B
KEGG:hsa:255488 RNF144B
Monarch:255488 RNF144B
NCBI Gene:255488 RNF144B
OMIM:618869 RNF144B
UCSC:Q7Z419 RNF144B
Reference Transcript
RefSeq:NM_182757.3 RNF144B
Other Identifiers
11731082_at
11731083_at
11751653_a_at
17005197
228153_PM_at
228153_at
235549_PM_at
235549_at
239704_PM_at
239704_at
255488
2897182
2897183
2897185
2897186
2897187
2897190
2897196
2897200
2897204
2897205
2897207
2897208
2897209
2897210
2897211
2897212
2897213
2897214
2897215
2897216
2897217
48276_at
56871_at
8117106
91747_at
A_24_P406060
GO:0000151
GO:0000209
GO:0003824
GO:0004842
GO:0005515
GO:0005737
GO:0005739
GO:0005829
GO:0006511
GO:0006915
GO:0008270
GO:0012501
GO:0016020
GO:0016567
GO:0016740
GO:0031624
GO:0031966
GO:0043066
GO:0043226
GO:0046872
GO:0061630
GO:0140096
HMNXSV003041710
Hs.164192.0.A1_3p_at
Hs.294092.0.A1_3p_at
Hs.87089.0.A1_3p_at
ILMN_1752526
PH_hs_0033313
TC06000120.hg
Participates
as a member of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
Rnf144b [cytosol]
(Rattus norvegicus)
RNF144B [cytosol]
(Bos taurus)
RNF144B [cytosol]
(Canis familiaris)
RNF144B [cytosol]
(Dictyostelium discoideum)
RNF144B [cytosol]
(Gallus gallus)
RNF144B [cytosol]
(Mus musculus)
RNF144B [cytosol]
(Sus scrofa)
rnf144b [cytosol]
(Xenopus tropicalis)
CG12339 [cytosol]
(Drosophila melanogaster)
Cross References
ENSEMBL
ENST00000259939
,
ENSP00000259939
,
ENSG00000137393
OpenTargets
ENSG00000137393
GeneCards
RNF144B
HPA
ENSG00000137393-RNF144B
PRO
Q7Z419
Pharos - Targets
Q7Z419
HMDB Protein
HMDBP11581
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14933 UBE2L6
2
UBE2L6 [cytosol]
(R-HSA-936014)
UBE2L6 [nucleoplasm]
(R-HSA-5653666)
0.681
4
UniProt:Q07812 BAX
3
BAX [mitochondrial outer membrane]
(R-HSA-139949)
BAX activated [cytosol]
(R-HSA-139907)
BAX [cytosol]
(R-HSA-139916)
0.556
5
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