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VPRBP [cytosol]
Stable Identifier
R-HSA-975984
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
DCAF1, Protein VPRBP, VPRBP_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
VPRBP [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y4B6 DCAF1
Gene Names
VPRBP, DCAF1, KIAA0800, RIP
Chain
chain:1-1507
Reference Genes
BioGPS Gene:9730 VPRBP
CTD Gene:9730 VPRBP
dbSNP Gene:9730 VPRBP
ENSEMBL:ENSG00000145041 VPRBP
HGNC:30911 VPRBP
KEGG Gene (Homo sapiens):9730 VPRBP
Monarch:9730 VPRBP
NCBI Gene:9730 VPRBP
UCSC:Q9Y4B6 VPRBP
Reference Transcript
RefSeq:XM_017007547.1 VPRBP
RefSeq:XM_011534277.2 VPRBP
RefSeq:XM_005276755.4 VPRBP
RefSeq:XM_011534274.2 VPRBP
RefSeq:XM_011534275.2 VPRBP
RefSeq:XM_005276753.4 VPRBP
RefSeq:XM_017007549.1 VPRBP
RefSeq:XM_017007546.1 VPRBP
RefSeq:NM_001171904.1 VPRBP
RefSeq:XM_011534273.2 VPRBP
RefSeq:NM_014703.2 VPRBP
RefSeq:XM_011534276.2 VPRBP
RefSeq:XM_017007550.1 VPRBP
RefSeq:XM_017007548.1 VPRBP
Other Identifiers
0004230019
11756398_a_at
11762378_a_at
16954576
204376_at
204377_s_at
226476_s_at
226477_at
226481_at
2675629
2675630
2675631
2675632
2675633
2675634
2675635
2675636
2675637
2675638
2675639
2675640
2675641
2675642
2675643
2675644
2675645
2675647
2675649
2675650
2675652
2675653
2675654
2675655
2675656
2675657
2675659
2675660
2675661
2675662
2675663
2675664
2675665
2675666
2675669
38873_at
53184_at
8087748
9730
A_23_P212595
A_24_P26170
A_24_P26177
GE81953
GO:0000122
GO:0000166
GO:0001650
GO:0002376
GO:0003674
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0006259
GO:0006325
GO:0006464
GO:0008134
GO:0008150
GO:0008180
GO:0009058
GO:0016032
GO:0016301
GO:0016310
GO:0016567
GO:0016740
GO:0030154
GO:0030183
GO:0030331
GO:0032991
GO:0033151
GO:0034641
GO:0035212
GO:0040007
GO:0043167
GO:0043226
GO:0044403
GO:0048856
GO:0051276
GO:0080008
GO:1990244
GO:1990245
Hs.118738.2.A1_3p_a_at
Hs.118738.2.A2_3p_at
ILMN_1660933
ILMN_2181089
PH_hs_0039428
TC03001436.hg
g7662315_3p_a_at
Participant Of
hasCandidate
E3 ligases in proteasomal degradation [cytosol]
Inferred To
VPRBP [cytosol] (Sus scrofa)
mahj [cytosol] (Drosophila melanogaster)
DCAF1 [cytosol] (Canis familiaris)
DCAF1 [cytosol] (Gallus gallus)
Dcaf1 [cytosol] (Mus musculus)
Dcaf1 [cytosol] (Rattus norvegicus)
dcaf1 [cytosol] (Xenopus tropicalis)
dcaf-1 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
XP_016863039.1
,
XP_016863035.1
,
XP_005276812.1
,
XP_011532576.1
,
XP_005276810.1
,
XP_016863036.1
,
XP_011532577.1
,
NP_001165375.1
,
XP_016863037.1
,
XP_011532579.1
,
XP_011532578.1
,
NP_055518.1
,
XP_016863038.1
,
XP_011532575.1
IntEnz
2.7.11.1
HPA
ENSG00000145041-DCAF1
GeneCards
Q9Y4B6
Ensembl
ENSP00000338857
,
ENST00000423656
,
ENSG00000145041
,
ENSP00000393183
,
ENSP00000421724
,
ENST00000504652
,
ENST00000335891
PRO
Q9Y4B6
PDB
6N45
,
5JK7
,
3WA0
,
4CC9
,
5AJA
,
4P7I
,
4PXW
,
4Z8L
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y3Z3 SAMHD1
1
SAMHD1 [nucleoplasm]
(R-HSA-5624198)
0.544
2
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