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ANAPC13 [cytosol]
Stable Identifier
R-HSA-975982
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
APC13, Anaphase-promoting complex subunit 13, APC13_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC13 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BS18 ANAPC13
Gene Names
ANAPC13
Chain
chain:1-74
Reference Genes
BioGPS Gene:25847 ANAPC13
COSMIC (genes):ANAPC13 ANAPC13
CTD Gene:25847 ANAPC13
dbSNP Gene:25847 ANAPC13
ENSEMBL:ENSG00000129055 ANAPC13
HGNC:24540 ANAPC13
KEGG:hsa:25847 ANAPC13
Monarch:25847 ANAPC13
NCBI Gene:25847 ANAPC13
OMIM:614484 ANAPC13
UCSC:Q9BS18 ANAPC13
Reference Transcript
RefSeq:NM_001242374.1 ANAPC13
RefSeq:NM_001242375.1 ANAPC13
RefSeq:NM_015391.3 ANAPC13
Other Identifiers
11716625_a_at
11754697_a_at
16959465
209001_PM_s_at
209001_s_at
215282_PM_at
215282_at
25847
2696380
2696381
2696382
2696383
2696384
2696386
2696387
2696388
2696389
2696390
2696391
38687_at
8090866
A_32_P16854
GE554395
GE55738
GO:0005515
GO:0005634
GO:0005680
GO:0007346
GO:0016567
GO:0030163
GO:0031145
GO:0043226
GO:0051301
GO:0051445
GO:0070936
GO:0070979
GO:0141198
HMNXSV003029508
ILMN_1793894
PH_hs_0005946
TC03001805.hg
g13529286_3p_a_at
Participates
as a component of
APC/C E3 ligase complex [cytosol] (Homo sapiens)
Inferred To
Anapc13 [cytosol]
(Mus musculus)
Anapc13 [cytosol]
(Rattus norvegicus)
BEST:GH01256 [cytosol]
(Drosophila melanogaster)
Ghost homologue of ANAPC13 [cytosol]
(Caenorhabditis elegans)
Ghost homologue of ANAPC13 [cytosol]
(Saccharomyces cerevisiae)
Ghost homologue of ANAPC13 [cytosol]
(Schizosaccharomyces pombe)
ANAPC13 [cytosol]
(Bos taurus)
ANAPC13 [cytosol]
(Canis familiaris)
ANAPC13 [cytosol]
(Dictyostelium discoideum)
ANAPC13 [cytosol]
(Gallus gallus)
ANAPC13 [cytosol]
(Sus scrofa)
anapc13 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001229303.1
,
NP_001229304.1
,
NP_056206.1
OpenTargets
ENSG00000129055
ENSEMBL
ENST00000514612
,
ENST00000511751
,
ENSP00000421760
,
ENSP00000346987
,
ENST00000354910
,
ENST00000510994
,
ENSP00000427327
,
ENSP00000421842
HPA
ENSG00000129055-ANAPC13
PRO
Q9BS18
Pharos - Targets
Q9BS18
PDB
4UI9
,
6TNT
,
5L9U
,
6TM5
,
6Q6G
,
8TAU
,
6Q6H
,
8TAR
,
5L9T
,
8S4G
,
7QE7
,
5G04
,
6TLJ
,
8PKP
,
5KHR
,
5LCW
,
5KHU
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9JJ66
3
Cdc20 [nucleoplasm]
(R-MMU-6783069)
Cdc20 [nucleoplasm]
(R-MMU-174112)
Cdc20 [cytosol]
(R-MMU-141412)
0.564
2
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
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