Reactome | B4GALT4 [Golgi membrane]

B4GALT4 [Golgi membrane]

Stable Identifier

R-HSA-975911

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Beta-1,4-galactosyltransferase 4, B4GT4_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - N-glycan antennae elongation in the medial/trans-Golgi (Homo sapiens)
        
        N-Glycan antennae elongation (Homo sapiens)
        
        Addition of galactose by beta 4-galactosyltransferases (Homo sapiens)
        
        B4GALT1-6 homodimers [Golgi membrane] (Homo sapiens)
        
        B4GALT4 homodimer [Golgi membrane] (Homo sapiens)
        
        B4GALT4 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:O60513 B4GALT4

Gene Names

B4GALT4, UNQ552/PRO1109

Chain

chain:1-344

Reference Genes

BioGPS Gene:8702 B4GALT4

COSMIC (genes):B4GALT4 B4GALT4

CTD Gene:8702 B4GALT4

dbSNP Gene:8702 B4GALT4

ENSEMBL:ENSG00000121578 B4GALT4

HGNC:927 B4GALT4

KEGG:hsa:8702 B4GALT4

Monarch:8702 B4GALT4

NCBI Gene:8702 B4GALT4

OMIM:604015 B4GALT4

UCSC:O60513 B4GALT4

Reference Transcript

Other Identifiers

11719785_s_at

11748913_a_at

16957738

210540_PM_s_at

210540_s_at

212876_PM_at

212876_at

2690775

2690777

2690778

2690779

2690780

2690781

2690782

2690783

2690784

2690785

2690789

2690795

2690796

2690797

2690798

2690799

2690800

2690801

2690802

2690803

2690804

2690805

2690806

2690807

2690808

2690809

2690810

2690811

39432_at

8089743

8702

A_32_P103945

GE55672

GO:0000139

GO:0001572

GO:0003824

GO:0003945

GO:0005515

GO:0005576

GO:0005794

GO:0005975

GO:0006486

GO:0006629

GO:0006643

GO:0006790

GO:0008378

GO:0016020

GO:0016740

GO:0016757

GO:0018146

GO:0032580

GO:0035250

GO:0043226

GO:0046872

GO:0070085

GO:1901135

HMNXSV003002451

HMNXSV003052019

Hs.13225.1.S2_3p_at

ILMN_1661500

ILMN_2380688

PH_hs_0001269

TC03001680.hg

g13325453_3p_a_at

Participates

as a component of

B4GALT4 homodimer [Golgi membrane] (Homo sapiens)

Inferred To

beta4GalNAcTB [Golgi membrane] (Drosophila melanogaster)

Homologues of B4GALT4 [Golgi membrane] (Drosophila melanogaster)

B4GALT4 [Golgi membrane] (Bos taurus)

B4GALT4 [Golgi membrane] (Canis familiaris)

B4GALT4 [Golgi membrane] (Gallus gallus)

B4GALT4 [Golgi membrane] (Mus musculus)

B4GALT4 [Golgi membrane] (Rattus norvegicus)

B4GALT4 [Golgi membrane] (Sus scrofa)

b4galt4 [Golgi membrane] (Danio rerio)

b4galt4 [Golgi membrane] (Xenopus tropicalis)

beta4GalNAcTA [Golgi membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENST00000393765, ENSP00000352144, ENSP00000377360, ENST00000483209, ENSG00000121578, ENST00000359213, ENSP00000420161

OpenTargets

ENSG00000121578

GeneCards

B4GALT4

HPA

ENSG00000121578-B4GALT4

PRO

O60513

Pharos - Targets

O60513

GlyGen

O60513

HMDB Protein

HMDBP01033

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11021 HSPA5	6	HSPA5 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985498) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [extracellular region] (R-HSA-351322)	0.527	2