Reactome | MGAT3 [Golgi membrane]

MGAT3 [Golgi membrane]

Stable Identifier

R-HSA-975897

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, MGAT3_HUMAN

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - N-glycan antennae elongation in the medial/trans-Golgi (Homo sapiens)
        
        Reactions specific to the hybrid N-glycan synthesis pathway (Homo sapiens)
        
        Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 (Homo sapiens)
        
        MGAT3 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q09327 MGAT3

Gene Names

MGAT3, GGNT3

Chain

chain:1-533

Reference Genes

BioGPS Gene:4248 MGAT3

COSMIC (genes):MGAT3 MGAT3

CTD Gene:4248 MGAT3

dbSNP Gene:4248 MGAT3

ENSEMBL:ENSG00000128268 MGAT3

HGNC:7046 MGAT3

KEGG:hsa:4248 MGAT3

Monarch:4248 MGAT3

NCBI Gene:4248 MGAT3

OMIM:604621 MGAT3

UCSC:Q09327 MGAT3

Reference Transcript

Other Identifiers

11722132_a_at

11722133_a_at

208058_PM_s_at

208058_s_at

209764_PM_at

209764_at

244104_PM_at

244104_at

345_at

3945866

3945873

3945874

4248

8073129

A_14_P104211

A_23_P91742

A_24_P245838

D13789_at

GE484935

GO:0000139

GO:0003824

GO:0003830

GO:0005515

GO:0005794

GO:0006044

GO:0006486

GO:0006487

GO:0008104

GO:0016020

GO:0016740

GO:0016757

GO:0030334

GO:0034599

GO:0043226

GO:0050435

GO:0050877

GO:0050890

GO:0140096

GO:1901135

GO:1902966

GO:1905166

HMNXSV003028642

Hs.112.1.A2_3p_at

Hs.212422.0.A1_3p_at

ILMN_1766475

ILMN_1853824

PH_hs_0023385

PH_hs_0038194

TC22000315.hg

g6031184_3p_a_at

Inferred To

gnt8 [Golgi membrane] (Dictyostelium discoideum)

MGAT3 [Golgi membrane] (Bos taurus)

MGAT3 [Golgi membrane] (Gallus gallus)

MGAT3 [Golgi membrane] (Sus scrofa)

mgat3 [Golgi membrane] (Xenopus tropicalis)

Mgat3 [Golgi membrane] (Drosophila melanogaster)

Mgat3 [Golgi membrane] (Mus musculus)

Mgat3 [Golgi membrane] (Rattus norvegicus)

Cross References

ENSEMBL

ENSG00000128268, ENST00000341184, ENSP00000345270

OpenTargets

ENSG00000128268

IntEnz

2.4.1.144

GeneCards

MGAT3

HPA

ENSG00000128268-MGAT3

ZINC target

Q09327

PRO

Q09327

Pharos - Targets

Q09327

GlyGen

Q09327

HMDB Protein

HMDBP01709

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BSL1 UBAC1	1	UBAC1 [cytosol] (R-HSA-8851644)	0.556	3

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