Reactome | ST6GAL2 [Golgi membrane]

ST6GAL2 [Golgi membrane]

Stable Identifier

R-HSA-975893

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Beta-galactoside alpha-2,6-sialyltransferase 2, SIAT2_HUMAN

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
      - Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
        
        Sialic acid metabolism (Homo sapiens)
        
        ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Homo sapiens)
        
        ST6GAL1,2 [Golgi membrane] (Homo sapiens)
        
        ST6GAL2 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96JF0 ST6GAL2

Gene Names

ST6GAL2, KIAA1877, SIAT2

Chain

chain:1-529

Reference Genes

BioGPS Gene:84620 ST6GAL2

COSMIC (genes):ST6GAL2 ST6GAL2

CTD Gene:84620 ST6GAL2

dbSNP Gene:84620 ST6GAL2

ENSEMBL:ENSG00000144057.16 ST6GAL2

HGNC:10861 ST6GAL2

KEGG Gene (Homo sapiens):84620 ST6GAL2

Monarch:84620 ST6GAL2

NCBI Gene:84620 ST6GAL2

OMIM:608472 ST6GAL2

UCSC:Q96JF0 ST6GAL2

Reference Transcript

Other Identifiers

11724382_a_at

11724383_at

1555123_PM_at

1555123_at

16901497

228821_PM_at

228821_at

2569218

2569219

2569220

2569221

2569222

2569223

2569224

2569228

2569229

2569230

2569236

2569237

2569238

2569239

2569249

2569252

2569253

2569254

47621_at

8054439

84620

A_23_P429425

A_32_P126157

A_33_P3331746

GE564510

GE80632

GO:0000139

GO:0003824

GO:0003835

GO:0005515

GO:0005794

GO:0005975

GO:0006486

GO:0008373

GO:0009311

GO:0016020

GO:0016740

GO:0016757

GO:0032580

GO:0036211

GO:0043226

GO:0097503

GO:1901135

HMNXSV003045919

HMNXSV003057216

Hs.98265.0.A1_3p_at

Hs2.98265.2.S1_3p_at

ILMN_1698432

ILMN_1797102

PH_hs_0005401

TC02002174.hg

Participates

as a member of

ST6GAL1,2 [Golgi membrane] (Homo sapiens)

Inferred To

SiaT [Golgi membrane] (Drosophila melanogaster)

st6gal2-r [Golgi membrane] (Danio rerio)

St6gal2 [Golgi membrane] (Mus musculus)

St6gal2 [Golgi membrane] (Rattus norvegicus)

st6gal2 [Golgi membrane] (Xenopus tropicalis)

ST6GAL2 [Golgi membrane] (Bos taurus)

ST6GAL2 [Golgi membrane] (Canis familiaris)

ST6GAL2 [Golgi membrane] (Gallus gallus)

ST6GAL2 [Golgi membrane] (Sus scrofa)

Cross References

RefSeq

NP_001309291.1, XP_006712865.1, XP_011510301.1, NP_001135824.1, XP_011510303.1, NP_115917.1, NP_001135823.1

OpenTargets

ENSG00000144057

HPA

ENSG00000144057-ST6GAL2

GeneCards

Q96JF0

Ensembl

ENST00000361686, ENSP00000387332, ENST00000409382, ENST00000409087, ENSG00000144057, ENSP00000386942, ENSP00000355273

PRO

Q96JF0

Pharos - Targets

Q96JF0

HMDB Protein

HMDBP11957

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