ASA- (GI) translocates from cytosol to extracellular region

Stable Identifier
R-HSA-9757441
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
cytosol, extracellular region
Synonyms
Acetylsalicylate localizes to extracellular space
ReviewStatus
5/5
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ASA- (GI) translocates from cytosol to extracellular region
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It is not known how acetylsalicylate (ASA-) localizes out of gastrointestinal cells. In particular, the ABCB1 efflux pump does not transport ASA- (Singh et al, 2020).
Literature References
PubMed ID Title Journal Year
32302241 Is aspirin a substrate of MDR1/P-glycoprotein?

Iyer, R, Naik, T, Chatterjee, S, Rajanna, P, Nigam, A, Shen, H, Singh, R

Xenobiotica 2020
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as an event of
Authored
Stephan, R  (2021-08-03)
Reviewed
Huddart, R  (2021-10-13)
Created
Stephan, R  (2021-11-01)
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