EOMES and TBXT (T, Brachyury) bind the SNAI1 gene

Stable Identifier
R-HSA-9756666
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Eomesodermin (EOMES) and TBXT (T, Brachyury) are expressed in mesoderm and endoderm progenitors in the primitive streak. In mesoderm progenitors EOMES and TBXT bind the promoter of the Snail1 (SNAI1) gene (inferred from mouse homologs). SNAI1 is a master regulator of epithelial to mesenchymal transition.
Participants
Participates
Inferred From
Authored
Reviewed
Created
Cite Us!