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PON3 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-9756394
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Serum paraoxonase/lactonase 3 ecNumber3.1.1.2/ecNumber ecNumber3.1.1.81/ecNumber ecNumber3.1.8.1/ecNumber, PON3_HUMAN
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Atorvastatin ADME (Homo sapiens)
PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV (Homo sapiens)
PON1,3:2xCa2+ dimers [endoplasmic reticulum membrane] (Homo sapiens)
PON3:2xCa2+ dimer [endoplasmic reticulum membrane] (Homo sapiens)
PON3 [endoplasmic reticulum membrane] (Homo sapiens)
PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV (Homo sapiens)
PON1,3:2xCa2+ dimers [endoplasmic reticulum membrane] (Homo sapiens)
PON3:2xCa2+ dimer [endoplasmic reticulum membrane] (Homo sapiens)
PON3 [endoplasmic reticulum membrane] (Homo sapiens)
PON1,3 hydrolyse ATVL to ATV (Homo sapiens)
PON1,3:2xCa2+ dimers [endoplasmic reticulum membrane] (Homo sapiens)
PON3:2xCa2+ dimer [endoplasmic reticulum membrane] (Homo sapiens)
PON3 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15166 PON3
Gene Names
PON3
Chain
chain:1-354, signal peptide:1-
Reference Genes
BioGPS Gene:5446 PON3
COSMIC (genes):PON3 PON3
CTD Gene:5446 PON3
dbSNP Gene:5446 PON3
ENSEMBL:ENSG00000105852 PON3
HGNC:9206 PON3
Monarch:5446 PON3
NCBI Gene:5446 PON3
OMIM:602720 PON3
UCSC:Q15166 PON3
Reference Transcript
RefSeq:NM_000940.2 PON3
Other Identifiers
11742503_a_at
11753074_a_at
17059911
213695_PM_at
213695_at
3061969
3061970
3061971
3061972
3061975
3061976
3061977
3061978
3061979
3061980
3061981
3061982
3061983
3061984
3061985
3061986
3061989
3061991
3061992
3061993
41424_at
5446
8141066
A_23_P215549
GE57783
GO:0003014
GO:0003096
GO:0003824
GO:0004063
GO:0004064
GO:0005576
GO:0005615
GO:0005789
GO:0009636
GO:0016787
GO:0032929
GO:0042803
GO:0043226
GO:0046395
GO:0046872
GO:0051649
GO:0070062
GO:0102007
GO:1901335
GO:2001038
HMNXSV003018671
Hs.296259.0.S1_3p_at
ILMN_1701007
L48516_at
PH_hs_0025821
TC07003068.hg
TC07003364.hg
Participates
as a component of
PON3:2xCa2+ dimer [endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
PON3 [extracellular region]
Inferred To
PON3 [endoplasmic reticulum membrane]
(Bos taurus)
PON3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
PON3 [endoplasmic reticulum membrane]
(Canis familiaris)
PON3 [endoplasmic reticulum membrane]
(Danio rerio)
PON3 [endoplasmic reticulum membrane]
(Gallus gallus)
PON3 [endoplasmic reticulum membrane]
(Mus musculus)
PON3 [endoplasmic reticulum membrane]
(Rattus norvegicus)
PON3 [endoplasmic reticulum membrane]
(Sus scrofa)
PON3 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
Homologues of PON3 [endoplasmic reticulum membrane]
(Danio rerio)
Cross References
Guide to Pharmacology - Targets
3054
ENSEMBL
ENST00000265627
,
ENSP00000265627
OpenTargets
ENSG00000105852
HPA
ENSG00000105852-PON3
PRO
Q15166
Pharos - Targets
Q15166
GlyGen
Q15166
Orphanet
PON3
HMDB Protein
HMDBP00089
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