Reactome | GABRR3 [plasma membrane]

GABRR3 [plasma membrane]

Stable Identifier

R-HSA-975454

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Gamma-aminobutyric acid receptor subunit rho-3, GBRR3_HUMAN

Locations in the PathwayBrowser

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Neuronal System (Homo sapiens)

- Transmission across Chemical Synapses (Homo sapiens)
  - Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
    - GABA receptor activation (Homo sapiens)
      - GABRR pentamers:GABA transports extracellular Cl- to cytosol (Homo sapiens)
        
        GABRR pentamers:GABA [plasma membrane] (Homo sapiens)
        
        GABRR pentamers [plasma membrane] (Homo sapiens)
        
        GABRR3 pentamer [plasma membrane] (Homo sapiens)
        
        GABRR3 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:A8MPY1 GABRR3

Gene Names

GABRR3

Chain

signal peptide:1-24, chain:25-467

Reference Genes

BioGPS Gene:200959 GABRR3

COSMIC (genes):GABRR3 GABRR3

CTD Gene:200959 GABRR3

dbSNP Gene:200959 GABRR3

ENSEMBL:ENSG00000183185 GABRR3

HGNC:17969 GABRR3

KEGG:hsa:200959 GABRR3

Monarch:200959 GABRR3

NCBI Gene:200959 GABRR3

OMIM:618668 GABRR3

UCSC:A8MPY1 GABRR3

Reference Transcript

RefSeq:NM_001105580.2 GABRR3

Other Identifiers

11742289_a_at

11742290_at

16956641

200959

234410_PM_at

234410_at

2685815

2685816

2685818

2685819

2685824

2685825

2685826

2685827

2685828

2685829

2685830

2685831

2685832

2685834

2685836

2685837

2685838

2685842

2685845

2685846

8089060

A_23_P69020

GE86594

GO:0004888

GO:0004890

GO:0005215

GO:0005216

GO:0005230

GO:0005254

GO:0005575

GO:0005886

GO:0006811

GO:0006821

GO:0007214

GO:0007268

GO:0016020

GO:0019904

GO:0022851

GO:0023052

GO:0030594

GO:0034220

GO:0034707

GO:0043005

GO:0045202

GO:0045211

GO:0055085

GO:0060089

GO:0098982

GO:1902476

GO:1902495

GO:1902711

HMNXSV003023624

Hs.272266.0.S1_3p_at

ILMN_1700949

TC03001600.hg

Participates

as a component of

GABRR3 pentamer [plasma membrane] (Homo sapiens)

Inferred To

exp-1 [plasma membrane] (Caenorhabditis elegans)

GABRR3 [plasma membrane] (Bos taurus)

GABRR3 [plasma membrane] (Rattus norvegicus)

GABRR3 [plasma membrane] (Sus scrofa)

Homologues of GABRR3 [plasma membrane] (Caenorhabditis elegans)

Homologues of GABRR3 [plasma membrane] (Drosophila melanogaster)

lgc-35 [plasma membrane] (Caenorhabditis elegans)

Rdl [plasma membrane] (Drosophila melanogaster)

Gabrr3 [plasma membrane] (Mus musculus)

Lcch3 [plasma membrane] (Drosophila melanogaster)

unc-49 [plasma membrane] (Caenorhabditis elegans)

gabrr3a [plasma membrane] (Danio rerio)

lgc-38 [plasma membrane] (Caenorhabditis elegans)

lgc-43 [plasma membrane] (Caenorhabditis elegans)

gabrr3 [plasma membrane] (Xenopus tropicalis)

gab-1 [plasma membrane] (Caenorhabditis elegans)

Cross References

Guide to Pharmacology - Targets

422

ENSEMBL

ENSG00000183185, ENSP00000420790, ENST00000472788

OpenTargets

ENSG00000183185

GeneCards

GABRR3

HPA

ENSG00000183185-GABRR3

PRO

A8MPY1

Pharos - Targets

A8MPY1

GlyGen

A8MPY1

HMDB Protein

HMDBP08214

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