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TBPL2 [nucleoplasm]
Stable Identifier
R-HSA-9754296
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
TATA box-binding protein-like 2, TBPL2_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Germ layer formation at gastrulation (Homo sapiens)
Expression of EOMES in the primitive streak (Homo sapiens)
p-2S-SMAD2,3:SMAD4:CTNNB1:TBPL2:FOXH1:SMAD3:POU5F1:NANOG:EOMES gene [nucleoplasm] (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
Expression of Goosecoid (GSC) in the primitive streak (Homo sapiens)
p-2S-SMAD2,3:SMAD4:TRIM33:CTNNB1:FOXH1:SMAD3:EOMES:TBPL2:GSC gene [nucleoplasm] (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
Expression of MIXL1 in the primitive streak (Homo sapiens)
p-2S-SMAD2,3:TRIM33:p-2S-SMAD2,3:SMAD4:CTNNB1:FOXH1:EOMES:TBPL2:MIXL1 gene [nucleoplasm] (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
Expression of TBXT (T, Brachyury) in the primitive streak (Homo sapiens)
LEF1,TCF7:CTNNB1:NANOG:TBPL2:TBXT gene [nucleoplasm] (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
LEF1 or TCF7 (TCF1), CTNNB1, and TBPL2 (TRF3) bind the TBXT (T, Brachyury) gene (Homo sapiens)
LEF1,TCF7:CTNNB1:NANOG:TBPL2:TBXT gene [nucleoplasm] (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:SMAD4, CTNNB1, and TBPL2 bind FOXH1:SMAD3:EOMES gene (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:SMAD4:CTNNB1:TBPL2:FOXH1:SMAD3:POU5F1:NANOG:EOMES gene [nucleoplasm] (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:SMAD4, p-2S-SMAD2,3:TRIM33, CTNNB1, EOMES, and TBPL2 bind FOXH1:SMAD3:GSC gene (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:SMAD4:TRIM33:CTNNB1:FOXH1:SMAD3:EOMES:TBPL2:GSC gene [nucleoplasm] (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33, p-2S-SMAD2,3:SMAD4, CTNNB1, EOMES, and TBPL2 bind FOXH1:MIXL1 gene (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33:p-2S-SMAD2,3:SMAD4:CTNNB1:FOXH1:EOMES:TBPL2:MIXL1 gene [nucleoplasm] (Homo sapiens)
TBPL2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6SJ96 TBPL2
Gene Names
TBPL2, TBP2, TRF3
Chain
chain:1-343
Reference Genes
BioGPS Gene:387332 TBPL2
COSMIC (genes):TBPL2 TBPL2
CTD Gene:387332 TBPL2
dbSNP Gene:387332 TBPL2
ENSEMBL:ENSG00000182521 TBPL2
ENSEMBL_homo_sapiens_GENE:ENSG00000182521.6 TBPL2
HGNC:19841 TBPL2
KEGG Gene (Homo sapiens):387332 TBPL2
Monarch:387332 TBPL2
NCBI Gene:387332 TBPL2
OMIM:608964 TBPL2
UCSC:Q6SJ96 TBPL2
Reference Transcript
RefSeq:NM_199047.2 TBPL2
Other Identifiers
11738485_at
16793277
3565786
3565787
3565790
3565791
3565792
3565793
3565794
3565795
3565797
387332
7979341
A_33_P3229818
GO:0001674
GO:0003677
GO:0005634
GO:0005737
GO:0006351
GO:0006352
GO:0006366
GO:0016251
GO:0043226
GO:0140223
HMNXSV003034687
ILMN_1694928
TC14001160.hg
Participates
as a component of
p-2S-SMAD2,3:SMAD4:TRIM33:CTNNB1:FOXH1:SMAD3:EOMES:TBPL2:GSC gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:TRIM33:p-2S-SMAD2,3:SMAD4:CTNNB1:FOXH1:EOMES:TBPL2:MIXL1 gene [nucleoplasm] (Homo sapiens)
p-2S-SMAD2,3:SMAD4:CTNNB1:TBPL2:FOXH1:SMAD3:POU5F1:NANOG:EOMES gene [nucleoplasm] (Homo sapiens)
LEF1,TCF7:CTNNB1:NANOG:TBPL2:TBXT gene [nucleoplasm] (Homo sapiens)
as an input of
p-2S-SMAD2,3:SMAD4, p-2S-SMAD2,3:TRIM33, CTNNB1, EOMES, and TBPL2 bind FOXH1:SMAD3:GSC gene (Homo sapiens)
p-2S-SMAD2,3:TRIM33, p-2S-SMAD2,3:SMAD4, CTNNB1, EOMES, and TBPL2 bind FOXH1:MIXL1 gene (Homo sapiens)
p-2S-SMAD2,3:SMAD4, CTNNB1, and TBPL2 bind FOXH1:SMAD3:EOMES gene (Homo sapiens)
LEF1 or TCF7 (TCF1), CTNNB1, and TBPL2 (TRF3) bind the TBXT (T, Brachyury) gene (Homo sapiens)
Cross References
RefSeq
NP_950248.1
OpenTargets
ENSG00000182521
GeneCards
Q6SJ96
HPA
ENSG00000182521-TBPL2
Ensembl
ENSP00000247219
,
ENST00000247219
,
ENSG00000182521
PRO
Q6SJ96
Pharos - Targets
Q6SJ96
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