Reactome | p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm]

p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm]

Stable Identifier

R-HSA-9754133

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Participants

members

Participates

as an output of

CDK4 inhibitors bind CDK4 (Homo sapiens)

This entity regulates

Negatively

Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Homo sapiens)

Inferred To

p-T172-CDK4:CCND1:CDK4 inhibitors (CCND1) [nucleoplasm] (Xenopus tropicalis)

p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Bos taurus)

p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Canis familiaris)

p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Danio rerio)

p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Drosophila melanogaster)

p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Mus musculus)

p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Rattus norvegicus)

p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Schizosaccharomyces pombe)

p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Sus scrofa)

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